Liquid composition for liquid heating-type thermal flavor inhaler

Abstract

The present invention relates to a liquid composition for a liquid heating-type flavor inhaler. A liquid composition for a liquid heating-type flavor inhaler of the present invention contains (1) propylene glycol and glycerol, (2) nicotine, (3) benzoic acid, and (4) one or more organic acids excluding benzoic acid. Another liquid composition for a liquid heating-type flavor inhaler of the present invention contains (1) propylene glycol and glycerol, (2) nicotine, and (4) one or more organic acids excluding benzoic acid.

1 . A liquid composition for a liquid heating-type flavor inhaler, comprising
 (1) propylene glycol and glycerol,   (2) nicotine,   (3) benzoic acid, and   (4) one or more organic acids excluding benzoic acid.   
     
     
         2 . The liquid composition according to  claim 1 , wherein a mole ratio of (2) nicotine to the total of (3) benzoic acid and (4) one or more organic acids excluding benzoic acid falls within a range of 1:0.85 to 1:1.15. 
     
     
         3 . The liquid composition according to  claim 1  comprising lactic acid as (4) one or more organic acids excluding benzoic acid. 
     
     
         4 . The liquid composition according to  claim 3  comprising, in addition to lactic acid, any one selected from tartaric acid, fumaric acid, levulinic acid, malonic acid, acetic acid, adipic acid, citric acid, malic acid, pyruvic acid, sorbic acid, and mixtures thereof as (4) one or more organic acids excluding benzoic acid. 
     
     
         5 . The liquid composition according to  claim 3  comprising, in addition to lactic acid, any one selected from tartaric acid, fumaric acid, levulinic acid, malonic acid, and mixtures thereof as (4) one or more organic acids excluding benzoic acid. 
     
     
         6 . The liquid composition according to  claim 3  comprising, in addition to lactic acid, tartaric acid as (4) one or more organic acids excluding benzoic acid. 
     
     
         7 . The liquid composition according to  claim 1 , wherein a mole ratio of (2) nicotine to (3) benzoic acid falls within a range of 1:0.7 to 1:0.15. 
     
     
         8 . The liquid composition according to  claim 1 , wherein a mole ratio of (2) nicotine to (4) one or more organic acids excluding benzoic acid falls within a range of 1:0.9 to 1:0.3. 
     
     
         9 . The liquid composition according to  claim 1 , wherein (4) one or more organic acids excluding benzoic acid have solubility in glycerol of 0.32 mol/kg or more in molality. 
     
     
         10 . The liquid composition according to  claim 1  comprising substantially no water. 
     
     
         11 . The composition according to  claim 1  further comprising a flavor. 
     
     
         12 . A method of preparing a liquid composition for a liquid heating-type flavor inhaler, comprising steps of:
 (i) preparing a solution (A) by dissolving nicotine and benzoic acid in propylene glycol;   (ii) preparing a solution (B) by dissolving lactic acid in glycerol;   (iii) preparing, as necessary, a solution (C) by dissolving one or more organic acids excluding benzoic acid and lactic acid in propylene glycol or glycerol; and   (iv) mixing solution (A), solution (B), and solution (C).   
     
     
         13 . A method of preparing a liquid composition for a liquid heating-type flavor inhaler, comprising steps of:
 (i) preparing a solution (A) by dissolving nicotine and benzoic acid in propylene glycol; and   (v) dissolving glycerol, lactic acid, and, as necessary, one or more organic acids excluding benzoic acid and lactic acid in solution (A).   
     
     
         14 . The method according to  claim 12  further comprising adding a flavor in a step after step (i). 
     
     
         15 . A liquid heating-type flavor inhaler comprising the liquid composition according to  claim 1 . 
     
     
         16 . A method of reducing a gunpowder-like odor of benzoic acid in a liquid composition for a heating-type flavor inhaler,
 wherein the liquid composition for a heating-type flavor inhaler comprises (1) propylene glycol and glycerol, (2) nicotine, and (3) benzoic acid,   the method comprising further incorporating (4) one or more organic acids excluding benzoic acid into the liquid composition for a heating-type flavor inhaler.   
     
     
         17 . The method according to  claim 16  comprising incorporating lactic acid as (4) one or more organic acids excluding benzoic acid. 
     
     
         18 . The method according to  claim 17  comprising incorporating, in addition to lactic acid, any one selected from tartaric acid, fumaric acid, levulinic acid, malonic acid, acetic acid, adipic acid, citric acid, malic acid, pyruvic acid, sorbic acid, and mixtures thereof as (4) one or more organic acids excluding benzoic acid. 
     
     
         19 . A liquid composition for a liquid heating-type flavor inhaler, comprising
 (1) propylene glycol and glycerol,   (2) nicotine, and   (4) one or more organic acids excluding benzoic acid.   
     
     
         20 . The liquid composition according to  claim 19 , wherein a mole ratio of (2) nicotine to (4) one or more organic acids excluding benzoic acid falls within a range of 1:0.85 to 1:1.15. 
     
     
         21 . The liquid composition according to  claim 19  comprising lactic acid as (4) one or more organic acids excluding benzoic acid. 
     
     
         22 . The liquid composition according to  claim 21  comprising, in addition to lactic acid, any one selected from tartaric acid, fumaric acid, levulinic acid, malonic acid, acetic acid, adipic acid, citric acid, malic acid, pyruvic acid, sorbic acid, and mixtures thereof as (4) one or more organic acids excluding benzoic acid. 
     
     
         23 . The liquid composition according to  claim 19 , wherein (4) one or more organic acids excluding benzoic acid have solubility in glycerol of 0.32 mol/kg or more in molality. 
     
     
         24 . A method of preparing a liquid composition for a liquid heating-type flavor inhaler, comprising steps of:
 (i′) preparing a solution (B) by dissolving lactic acid in glycerol;   (ii′) preparing, as necessary, a solution (C) by dissolving one or more organic acids excluding benzoic acid and lactic acid in propylene glycol or glycerol; and   (iii′) mixing nicotine, solution (B), and solution (C).   
     
     
         25 . The method according to  claim 24  further comprising adding a flavor. 
     
     
         26 . A liquid heating-type flavor inhaler comprising the liquid composition according to  claim 19 .