Liquid oral composition

Abstract

The disclosure provides liquid compositions configured for oral use, the liquid composition comprising water in an amount of about 40% by weight or higher, based on total weight of the composition, a flavoring agent or an active ingredient or both a flavoring agent and an active ingredient, and one or more additional components selected from the group consisting of sweeteners, humectants, and alkali metal salts, wherein the composition has a water activity (Aw) of about 0.85 or lower. The liquid compositions are generally suitable for spraying into the oral cavity.

1 . A liquid composition, comprising: water in an amount of about 40% by weight or higher, based on total weight of the composition, a flavoring agent or an active ingredient or both a flavoring agent and an active ingredient, and one or more additional components selected from the group consisting of sweeteners, humectants, and alkali metal salts, wherein the composition has a water activity (Aw) of about 0.85 or lower. 
     
     
         2 . The composition of  claim 1 , wherein the one or more additional components selected from the group consisting of sweeteners, humectants, and alkali metal salts are present in a total amount of about 30% by weight or higher, based on total weight of the composition. 
     
     
         3 . The composition of  claim 2 , wherein the one or more additional components selected from the group consisting of sweeteners, humectants, and alkali metal salts are present in a total amount of about 35% by weight or higher, based on total weight of the composition. 
     
     
         4 . The composition of  claim 3 , wherein the one or more additional components selected from the group consisting of sweeteners, humectants, and alkali metal salts are present in a total amount of about 40% by weight or higher, based on total weight of the composition. 
     
     
         5 . The composition of  claim 1 , wherein the one or more additional components comprises at least one alkali metal salt and at least one sweetener. 
     
     
         6 . The composition of  claim 1 , wherein the one or more additional components comprises at least one humectant. 
     
     
         7 . The composition of  claim 1 , wherein the one or more additional components comprises (i) at least one alkali metal salt selected from sodium chloride, sodium carbonate, sodium bicarbonate, and combinations thereof; (ii) at least one sugar alcohol; and (iii) at least one humectant. 
     
     
         8 . The composition of  claim 1 , wherein the one or more additional components comprises (i) an alkali metal salt selected from sodium chloride and sodium carbonate; (ii) at least one sugar alcohol selected from xylitol and sorbitol; and (iii) at least one humectant selected from glycerin and propylene glycol. 
     
     
         9 . The composition of  claim 8 , further comprising at least one artificial sweetener. 
     
     
         10 . The composition of  claim 1 , wherein the water content of the composition is about 40 to about 60% by weight. 
     
     
         11 . The composition of  claim 1 , comprising an aqueous tobacco extract. 
     
     
         12 . The composition of  claim 1 , wherein the active ingredient is selected from the group consisting of a nicotine component, botanicals, nutraceuticals, stimulants, amino acids, vitamins, cannabinoids, cannabimimetics, terpenes, and combinations thereof. 
     
     
         13 . The composition of  claim 1 , comprising from about 0.001 to about 10% by weight of a nicotine component, calculated as the free base and based on the total weight of the composition. 
     
     
         14 . The composition of  claim 1 , wherein the composition is substantially free of tobacco material, excluding any nicotine component present. 
     
     
         15 . The composition of  claim 1 , wherein the composition has a water activity (Aw) of about 0.70 to about 0.85. 
     
     
         16 . The composition of  claim 1 , wherein the composition has a pH of about 7 or greater. 
     
     
         17 . The composition of  claim 16 , wherein the composition has a pH of about 7 to about 9. 
     
     
         18 . The composition of  claim 1 , wherein the composition is adapted for spraying into the oral cavity. 
     
     
         19 . The composition of  claim 1 , comprising:
 about 40 to about 60% by weight water;   about 20 to about 30% by weight of one or more sugar alcohols;   about 10 to about 20% by weight of one or more humectants;   about 3 to about 10% by weight of one or more alkali metal salts; and   about 0.001 to about 10% by weight of one or more active ingredients, flavoring agents, or combinations thereof;   wherein the composition has a water activity (Aw) of about 0.70 to about 0.85.   
     
     
         20 . The composition of  claim 1 , comprising:
 about 40 to about 60% by weight water;   about 20 to about 30% by weight of one or more sugar alcohols;   about 10 to about 20% by weight of one or more humectants;   about 3 to about 10% by weight of one or more alkali metal salts; and   about 0.001 to about 10% by weight of an active ingredient selected from the group consisting of a nicotine component, botanicals, nutraceuticals, stimulants, amino acids, vitamins, cannabinoids, cannabimimetics, terpenes, and combinations thereof,   wherein the composition has a water activity (Aw) of about 0.70 to about 0.85.   
     
     
         21 .- 22 . (canceled)