Patient ratio adjustment for fluid delivery determination

Abstract

A system for controlling fluid delivery includes one or more processors, and one or more processor-readable storage media storing instructions which, when executed by the one or more processors, cause performance of: identifying a residual value indicative of a difference between a first value and a second value, the first value corresponding to a physiological condition of a patient before delivery of a bolus amount of fluid, and the second value corresponding to a physiological condition of the patient after delivery of the bolus amount of the fluid, determining a ratio adjustment factor based on the residual value, and determining, based on the ratio adjustment factor, an updated value for a ratio that influences delivery of bolus amounts of the fluid.

What is claimed is: 
     
         1 . A system for controlling fluid delivery, the system comprising:
 one or more processors; and   one or more processor-readable storage media storing instructions which, when executed by the one or more processors, cause performance of:
 identifying a residual value indicative of a difference between a first value and a second value, the first value corresponding to a physiological condition of a patient before delivery of a bolus amount of fluid, and the second value corresponding to a physiological condition of the patient after delivery of the bolus amount of the fluid; 
 determining a ratio adjustment factor based on the residual value; and 
 determining, based on the ratio adjustment factor, an updated value for a ratio that influences delivery of bolus amounts of the fluid. 
   
     
     
         2 . The system of  claim 1 , wherein the bolus amount of fluid is a first bolus amount of fluid, and wherein the one or more processor-readable storage media further store instructions which, when executed by the one or more processors, cause performance of:
 generating information indicative of a second bolus amount of fluid based on the updated value for the ratio.   
     
     
         3 . The system of  claim 2 , wherein generating information indicative of the second bolus amount of fluid based on the updated value for the ratio comprises generating information indicative of the second bolus amount of fluid based on the updated value for the ratio and an input carbohydrate amount. 
     
     
         4 . The system of  claim 1 , wherein the one or more processor-readable storage media further store instructions which, when executed by the one or more processors, cause performance of:
 storing the updated value for the ratio.   
     
     
         5 . The system of  claim 1 , wherein the bolus amount of fluid is influenced by a previous value for the ratio, and wherein determining, based on the ratio adjustment factor, the updated value for the ratio comprises:
 scaling the previous value by the ratio adjustment factor to determine the updated value for the ratio.   
     
     
         6 . The system of  claim 1 , wherein the one or more processor-readable storage media further store instructions which, when executed by the one or more processors, cause performance of:
 determining the bolus amount of fluid based on an input carbohydrate amount and a previous value for the ratio.   
     
     
         7 . The system of  claim 1 , wherein the first value comprises a pre-prandial value of the physiological condition, and the second value comprises a post-prandial value of the physiological condition after metabolization of the bolus amount of the fluid. 
     
     
         8 . The system of  claim 1 , wherein determining the ratio adjustment factor based on the residual value comprises:
 determining a residual amount of the fluid after metabolization of the bolus amount based on the residual value; and   determining a ratio of the bolus amount to a sum of the bolus amount and the residual amount of the fluid after metabolization of the bolus amount.   
     
     
         9 . The system of  claim 8 , wherein determining the residual amount of the fluid comprises dividing the residual value by a fluid sensitivity factor of the patient. 
     
     
         10 . The system of  claim 1 , wherein determining the ratio adjustment factor based on the residual value comprises:
 determining a residual amount of carbohydrates based on the residual value;   determining a ratio of a difference between an input amount of carbohydrates and the residual amount of carbohydrates to the input amount of carbohydrates.   
     
     
         11 . The system of  claim 10 , wherein determining the residual amount of carbohydrates comprises dividing the residual value by a carbohydrate conversion factor. 
     
     
         12 . The system of  claim 1 , wherein the fluid comprises insulin, wherein the physiological condition comprises a glucose level, wherein the residual value comprises a residual glucose value representing a difference between:
 a pre-bolus glucose level; and   a post-bolus and insulin metabolization glucose level.   
     
     
         13 . The system of  claim 1 , wherein the residual value comprises a residual glucose value representing an amount that the bolus amount overcompensated or undercompensated for an amount of carbohydrates. 
     
     
         14 . The system of  claim 13 , wherein the updated value comprises an updated carbohydrate ratio adjusted to compensate for the residual glucose value. 
     
     
         15 . A processor-implemented method for controlling insulin delivery, the method comprising:
 identifying a residual value indicative of a difference between a first value and a second value, the first value corresponding to a physiological condition of a patient before delivery of a bolus amount of fluid, and the second value corresponding to a physiological condition of the patient after delivery of the bolus amount of the fluid;   determining a ratio adjustment factor based on the residual value; and   determining, based on the ratio adjustment factor, an updated value for a ratio that influences delivery of bolus amounts of the fluid.   
     
     
         16 . The method of  claim 15 , further comprising:
 generating information indicative of a second bolus amount of fluid based on the updated value for the ratio.   
     
     
         17 . The method of  claim 16 , wherein generating information indicative of the second bolus amount of fluid based on the updated value for the ratio comprises generating information indicative of the second bolus amount of fluid based on the updated value for the ratio and an input carbohydrate amount. 
     
     
         18 . The method of  claim 15 , further comprising:
 storing the updated value for the ratio.   
     
     
         19 . The method of  claim 15 , wherein the bolus amount of fluid is influenced by a previous value for the ratio, and wherein determining, based on the ratio adjustment factor, the updated value for the ratio comprises:
 scaling the previous value by the ratio adjustment factor to determine the updated value for the ratio.   
     
     
         20 . One or more non-transitory processor-readable storage media storing instructions which, when executed by one or more processors, cause performance of:
 identifying a residual value indicative of a difference between a first value and a second value, the first value corresponding to a physiological condition of a patient before delivery of a bolus amount of fluid, and the second value corresponding to a physiological condition of the patient after delivery of the bolus amount of the fluid;   determining a ratio adjustment factor based on the residual value; and   determining, based on the ratio adjustment factor, an updated value for a ratio that influences delivery of bolus amounts of the fluid.