US2022241404A1PendingUtilityA1

Mixed allergen compositions and methods for using the same

Assignee: UNIV LELAND STANFORD JUNIORPriority: Feb 20, 2015Filed: Sep 17, 2021Published: Aug 4, 2022
Est. expiryFeb 20, 2035(~8.6 yrs left)· nominal 20-yr term from priority
Inventors:Kari C. Nadeau
A61K 35/747A61K 9/0053A61K 2039/57A61K 39/35A61K 2035/115A61K 47/46A61K 2039/70A61K 47/44A61K 45/06A61K 2039/54A61K 2039/572A61K 2039/542A61K 35/60A61K 9/148A61K 2039/575A61K 2039/55
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Claims

Abstract

Mixed allergen compositions of one, two or more different allergens are provided. In some instances, the mixed allergen compositions include: a nut allergen; an animal allergen; and at least one of: a non-nut plant allergen; a biotic agent; and a vitamin. Also provided are methods of administering the mixed allergen compositions to a subject. The mixed allergen compositions find use in a variety of applications, including health maintenance, immune balance, gut balance, immune support, health improvement and therapeutic applications.

Claims

exact text as granted — not AI-modified
1 - 12 . (canceled) 
     
     
         13 . A method for preventing one or more food allergies in a subject in need thereof, the method comprising administering to the subject a mixed allergen composition comprising:
 2 to 20 different protein allergens, wherein at least one protein allergen is a nut allergen selected from the group consisting of peanut, almond, walnut, cashew, hazelnut, pecan, and pistachio, at least one protein allergen is an animal allergen selected from the group consisting of shrimp, cod, and salmon, and the mixed allergen composition comprises equal parts by protein weight of each protein allergen, and wherein the composition is administered to the subject at least weekly or at least every other week administration.   
     
     
         14 . The method of  claim 13 , wherein the mixed allergen composition further comprises a vitamin selected from the group consisting of vitamin D and vitamin C. 
     
     
         15 . The method of  claim 13 , further comprising allowing sufficient time for the administration of the composition to prevent one or more food allergies in the human subject. 
     
     
         16 . The method  claim 13 , wherein the one or more food allergies is a single food allergy. 
     
     
         17 . The method of  claim 13 , wherein the one or more food allergies is a multiple food allergy. 
     
     
         18 . The method of  claim 13 , wherein the 2 to 20 different protein allergens comprise at least one of shellfish, peanut, tree nut, fish, milk, egg, legume, grain, sesame, and fruit. 
     
     
         19 . The method of  claim 18 , wherein the 2 to 20 different protein allergens comprise at least one of cashew, pistachio, walnut, almond, pecan, chicken egg, cow milk, peanut, shrimp, salmon, wheat, cod, crab, soy, and sesame. 
     
     
         20 . The method of  claim 18 , wherein the composition is a food product. 
     
     
         21 . The method of  claim 20 , wherein the food product is pureed food product. 
     
     
         22 . The method of  claim 20 , wherein the food product is infant formula. 
     
     
         23 . The method of  claim 13 , wherein the administration of the composition prevents one or more food allergies in the subject as compared to administering to the subject a composition that includes only one protein allergen. 
     
     
         24 . The method of  claim 13 , wherein the human subject is a pediatric subject. 
     
     
         25 . The method of  claim 23 , wherein the pediatric subject is 1 month to 7 years old. 
     
     
         26 . The method of  claim 13 , wherein at least one protein allergen is a non-nut plant allergen selected from the group consisting of wheat, sesame, and oat. 
     
     
         27 . The method of  claim 13 , wherein at least one protein allergen is hen's egg. 
     
     
         28 . The method of  claim 13 , wherein at least one protein allergen is soy. 
     
     
         29 . The method of  claim 13 , wherein the mixed allergen composition comprises vitamin D.

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