US2022218665A1PendingUtilityA1

Methods and compositions for improving cognitive function

Assignee: UNIV JOHNS HOPKINSPriority: Oct 16, 2008Filed: Aug 17, 2021Published: Jul 14, 2022
Est. expiryOct 16, 2028(~2.2 yrs left)· nominal 20-yr term from priority
A61K 31/4015A61K 31/20A61P 25/28A61P 25/00A61P 43/00A61P 35/00A61K 31/19
71
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Claims

Abstract

This invention relates to treating age-related cognitive impairment. This invention in particular relates to the use of inhibitors of synaptic vesicle protein 2A (SV2A), such as levetiracetam, seletracetam, and brivaracetam, in improving cognitive function in subjects that exhibit age-related cognitive impairment or are at risk thereof, including, without limitation, subjects having or at risk for Mild Cognitive Impairment (MCI), Age-related Cognitive Decline (ARCD) or Age-Associated Memory Impairment (AAMI).

Claims

exact text as granted — not AI-modified
1 - 23 . (canceled) 
     
     
         24 . A pharmaceutical composition comprising 125 mg-250 mg levetiracetam, or a pharmaceutically acceptable salt thereof, wherein the levetiracetam, or the pharmaceutically acceptable salt thereof, in the pharmaceutical composition is formulated in unit dosage form for extended release and oral, once-a-day administration. 
     
     
         25 - 46 . (canceled)

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