Oral Care Compositions

Abstract

An oral care composition comprising primarily insoluble forms of zinc compounds and stannous compounds, as well as methods of using the same in the treatment or prevention of gingivitis, plaque, and dental caries.

1 . An oral care composition comprising an orally acceptable carrier, an insoluble stannous compound, and an insoluble zinc compound, wherein the composition comprises less than 30% soluble stannous as a fraction of total stannous by weight, and less than 30% soluble zinc as a fraction of total zinc by weight. 
     
     
         2 . The composition according to  claim 1 , wherein the composition is a high-water oral care composition. 
     
     
         3 . The composition according to  claim 1 , wherein the insoluble zinc compound is selected from one or more of zinc oxide, zinc phosphate, zinc pyrophosphate, zinc silicate, zinc oleate, zinc hydroxide, zinc carbonate, zinc peroxide and zinc sulfide. 
     
     
         4 . The composition according to  claim 1 , wherein the insoluble stannous compound is selected from one or more of stannous phosphate, stannous pyrophosphate, stannous oxide, stannous sulfate, stannous peroxide, and stannous hydroxide. 
     
     
         5 . (canceled) 
     
     
         6 . (canceled) 
     
     
         7 . (canceled) 
     
     
         8 . (canceled) 
     
     
         9 . The composition according to  claim 1 , wherein the composition is formulated by combining a soluble stannous compound with a precipitating agent to form the insoluble stannous compound during manufacture of the composition. 
     
     
         10 . An oral care composition made by combining an insoluble stannous compound and an insoluble zinc compound in an orally acceptable carrier. 
     
     
         11 . The composition according to  claim 10 , wherein the insoluble zinc compound is selected from one or more of zinc oxide, zinc phosphate, zinc pyrophosphate, zinc silicate, zinc oleate, zinc hydroxide, zinc carbonate, zinc peroxide and zinc sulfide. 
     
     
         12 . The composition according to  claim 10 , wherein the insoluble stannous compound is selected from one or more of stannous phosphate, stannous pyrophosphate, stannous oxide, stannous sulfate, stannous peroxide, and stannous hydroxide. 
     
     
         13 . The composition according to  claim 1 , wherein the composition comprises the insoluble zinc compound in an amount of from 0.05 to 10% by weight, relative to the weight of the oral care composition. 
     
     
         14 . The composition according to  claim 1 , wherein the composition comprises the insoluble stannous compound in an amount of from 0.05 to 10% by weight, relative to the weight of the oral care composition. 
     
     
         15 . The composition according to  claim 1 , wherein the amount of the water is 10% by weight or more, relative to the weight of the oral care composition. 
     
     
         16 . The composition according to  claim 1 , wherein the composition comprises less than 30% soluble stannous by weight of total stannous. 
     
     
         17 . The composition according to  claim 1 , wherein the composition comprises less than 30% soluble zinc by weight of total zinc. 
     
     
         18 . The composition according to  claim 1 , wherein the composition further comprises a polymeric rheological modifier, for example, an anionic polymer. 
     
     
         19 . The composition according to  claim 18 , wherein the anionic polymer is selected from the group consisting of synthetic anionic polymeric polycarboxylates, polyacrylic acids, polyphosphonic acids, and cross-linked carboxyvinyl copolymers. 
     
     
         20 . The composition according to  claim 19 , wherein the composition comprises an anionic polymeric polycarboxylate, optionally wherein the anionic polymeric polycarboxylate is selected from a modified cellulose polymer or a gum. 
     
     
         21 . The composition according to  claim 18 , wherein the polymeric rheological modifier is present in an amount of 1 to 20% by weight of the composition. 
     
     
         22 . The composition according to  claim 1 , wherein the oral care composition is a dentifrice, powder, cream, strip or gum. 
     
     
         23 . A method of treatment or prevention of gingivitis, plaque, and/or dental caries, the method comprising the application to the oral cavity of a person in need thereof a composition according to  claim 1 . 
     
     
         24 . (canceled)