Methods of treating or alleviating mental disorders and associated symptoms

Abstract

The present invention relates generally to methods for the treatment and/or prophylaxis of mental illness involving administration of 10-HDA. More particularly, methods are taught herein for the treatment and/or prophylaxis of obsessive compulsive disorder, anxiety disorder or a condition characterised by one or more symptoms of a obsessive compulsive disorder or an anxiety disorder.

1 .- 31 . (canceled) 
     
     
         32 . A method for the treatment of obsessive compulsive disorder, comprising administering to a mammal in need thereof an effective amount of 10-hydroxy-2-decenoic acid or a pharmaceutically acceptable salt thereof. 
     
     
         33 . The method according to  claim 32 , comprising administering an effective amount of trans 10-hydroxy-2-decenoic acid or a pharmaceutically acceptable salt thereof. 
     
     
         34 . The method according to  claim 32 , comprising administering an effective amount of cis 10-hydroxy-2-decenoic acid or a pharmaceutically acceptable salt thereof. 
     
     
         35 . The method according to  claim 32 , comprising administering an effective amount of a racemic mixture of trans and cis 10-hydroxy-2-decenoic acid or pharmaceutically acceptable salts thereof. 
     
     
         36 . The method according to  claim 32 , wherein the obsessive compulsive disorder is selected from the group consisting of obsessive compulsive disorder (OCD), body dysmorphic disorder, hoarding disorder, trichotillomania, excoriation disorder, substance/medication-induced obsessive-compulsive, and unspecified obsessive-compulsive disorder. 
     
     
         37 . The method according to  claim 32 , wherein the treatment alleviates one or more behavioural disturbances selected from obsessions, compulsions, and repetitive behavioural patterns. 
     
     
         38 . The method according to  claim 32 , wherein the 10-hydroxy-2-decenoic acid or a pharmaceutically acceptable salt thereof is administered as a composition. 
     
     
         39 . The method according to  claim 38 , wherein the composition comprises royal jelly, an extract of royal jelly, or a composition derived from royal jelly. 
     
     
         40 . The method according to  claim 32 , wherein the 10-hydroxy-2-decenoic acid or a pharmaceutically acceptable salt thereof is administered in a dosage in the range of 0.01 to 6000 mg/day, 0.1 to 5000 mg/day, 1 to 4000 mg/day, 10 to 3000 mg/day, 100 to 2000 mg/day, or 500 to 1500 mg/day. 
     
     
         41 . The method according to  claim 32 , wherein the 10-hydroxy-2-decenoic acid or a pharmaceutically acceptable salt thereof is administered in a dosage selected from 0.5 mg/day, 1 mg/day, 5 mg/day, 10 mg/day, 50 mg/day, 100 mg/day, 250 mg/day, 500 mg/day, 750 mg/day, 1000 mg/day, 1500 mg/day, and 2000 mg/day. 
     
     
         42 . The method according to  claim 32 , wherein the mammal is a human.