Prefilled medication device, method of making and using the same

Abstract

The invention generally relates to prefilled disposable medication devices, method of making, and using to store, contain and deliver at least a diluent for allergenic extract and more particularly to a prefilled cartridge containing a diluent for allergenic extract for use with an injection pen for allergy treatments.

1 - 73 . (canceled) 
     
     
         74 . A prefilled cartridge apparatus for use with an injection device, comprising:
 a cap comprising an interior portion including a self-healing material configured to allow a needle to be inserted through the self-healing material in order to add and subtract fluid into the prefilled cartridge, wherein the cap comprises a color code indicative of a predetermined concentration of at least one antigen;   a prefilled cartridge comprising a first end, a second end, and an internal lumen extending from the first end to the second end, wherein the first end is closed with the cap and the second end is open; and   a plunger arranged within a portion of the internal lumen of the prefilled cartridge, wherein the plunger is configured to move from a first position to a second position upon application of an external force provided by the injection device, and   wherein the prefilled cartridge comprises a fluid comprising a first predetermined volume of diluent for an allergenic extract.   
     
     
         75 . The apparatus of  claim 74 , wherein the prefilled cartridge is disposable. 
     
     
         76 . The apparatus of  claim 74 , wherein the diluent comprises 0.4% phenol. 
     
     
         77 . The apparatus of  claim 74 , further comprising one or more sensors configured to determine at least one of a temperature of the fluid, a flow rate of an injection of the prefilled cartridge in operation, and a characteristic indicative of use of the prefilled cartridge. 
     
     
         78 . The apparatus of  claim 74 , wherein the prefilled cartridge comprises a material selected from the group consisting of glass, plastic, thermoplastic, tempered glass, metal, alloy, composite, and combinations thereof. 
     
     
         79 . The apparatus of  claim 74 , wherein an internal surface of the prefilled cartridge comprises a hydrophilic coating. 
     
     
         80 . A prefilled cartridge apparatus for use with an injection device, comprising:
 a cap comprising an interior portion including a self-healing material configured to allow a needle to be inserted through the self-healing material in order to add and subtract fluid into the prefilled cartridge, wherein the cap comprises a color code indicative of a predetermined concentration of at least one antigen;   a prefilled cartridge comprising a first end, a second end, and an internal lumen extending from the first end to the second end, wherein the first end is closed with the cap and the second end is open; and   a piston arranged within a portion of the internal lumen of the prefilled cartridge, wherein the piston is configured to move from a first position to a second position upon application of an external force provided by the injection device, and   wherein the prefilled cartridge comprises a acrylonitrile butadiene styrene (ABS) fluid, and   wherein the prefilled cartridge is configured to receive a predetermined volume of an allergenic extract concentrate configured to elicit an immune response in a patient.   
     
     
         81 . The apparatus of  claim 80 , further comprising an injection device configured to receive the prefilled cartridge. 
     
     
         82 . The apparatus of  claim 80 , wherein an internal volume of the prefilled cartridge is about 3 ml or less. 
     
     
         83 . The apparatus of  claim 80 , wherein a volume of the acrylonitrile butadiene styrene (ABS) fluid is in a range from about ml to about 1 ml to about 3 ml. 
     
     
         84 . The apparatus of  claim 80 , wherein the color code includes one of a red color, a yellow color, a green color, a blue color and a silver color. 
     
     
         85 . The apparatus of  claim 80 , further comprising a radio frequency identification (RFID) tag. 
     
     
         86 . The apparatus of  claim 85 , wherein the radio frequency identification RFID tag is an active tag. 
     
     
         87 . A prefilled cartridge apparatus for use with an injection device, comprising:
 a cap comprising an interior portion including a self-healing material configured to allow a needle to be inserted through the self-healing material in order to add and subtract fluid into the prefilled cartridge, wherein the cap comprises a color code indicative of a predetermined concentration of an immunotherapy treatment;   a prefilled cartridge comprising a first end, a second end, and an internal lumen extending from the first end to the second end, wherein the first end is closed with the cap and the second end is open; and   a stopper arranged within a portion of the internal lumen of the prefilled cartridge, wherein the stopper is configured to move from a first position to a second position upon application of an external force provided by the injection device, wherein the prefilled cartridge comprises a acrylonitrile butadiene styrene (ABS) fluid;   one or more sensors configured to obtain a characteristic indicative of use of the prefilled cartridge; and   a wireless communication device configured to transmit information from the one or more sensors.   
     
     
         88 . The apparatus of  claim 87 , wherein the immunotherapy treatment comprises one or more of a tree pollen vector allergen, grass pollen vector allergen, weed pollen vector allergen, mold vector allergen and other vector allergen. 
     
     
         89 . The apparatus of  claim 88 , wherein the tree pollen vector allergen comprises one or more of a birch allergen, oak allergen and alder allergen. 
     
     
         90 . The apparatus of  claim 88 , wherein the immunotherapy treatment is a custom treatment for a patient. 
     
     
         91 . The apparatus of  claim 88 , wherein the stopper comprises a thermoplastic material. 
     
     
         92 . The apparatus of  claim 88 , further comprising an injection device configured to receive the prefilled cartridge.