US2022049233A1PendingUtilityA1

Novel mad nucleases

Assignee: INSCRIPTA INCPriority: Dec 10, 2019Filed: Nov 3, 2021Published: Feb 17, 2022
Est. expiryDec 10, 2039(~13.4 yrs left)· nominal 20-yr term from priority
C12N 15/102C12N 9/22C12N 2310/20C12N 15/113C12N 2800/80C12N 15/111C12N 15/907C12N 15/902
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Claims

Abstract

The present disclosure provides new RNA-guided nucleases for making rational, direct edits to nucleic acids in live cells.

Claims

exact text as granted — not AI-modified
We claim: 
     
         1 . A nuclease configured to perform nucleic acid-guided nuclease editing, wherein the nuclease is selected from a nuclease system comprising SEQ ID NO. 2, SEQ ID NO. 3, SEQ ID NO. 4, SEQ ID NO. 5, and SEQ ID NO. 6. 
     
     
         2 . The nuclease of  claim 1  comprising SEQ ID NO. 2. 
     
     
         3 . The nuclease of  claim 1  comprising SEQ ID NO. 3. 
     
     
         4 . The nuclease of  claim 1  comprising SEQ ID NO. 4. 
     
     
         5 . The nuclease of  claim 1  comprising SEQ ID NO. 5. 
     
     
         6 . The nuclease of  claim 1  comprising SEQ ID NO. 6.

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