US2021381982A1PendingUtilityA1

Medium For Resin Particles Containing Fluorescent Dye

Assignee: KONICA MINOLTA INCPriority: Apr 23, 2014Filed: Aug 20, 2021Published: Dec 9, 2021
Est. expiryApr 23, 2034(~7.7 yrs left)· nominal 20-yr term from priority
G01N 33/545G01N 21/64G01N 33/582C09K 11/025G01N 21/59C08K 5/3437C09K 11/06G01N 21/6428C09K 2211/1433C09K 2211/1416G01N 2021/6439
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Claims

Abstract

An object of the present invention is to provide a medium which is capable of inhibiting precipitation and/or aggregation of fluorescent dye-containing resin particles and enables to use the fluorescent dye-containing resin particles for staining after a long-term storage without having to perform complicated operations. The present invention provides a medium for storing fluorescent dye-containing resin particles, wherein, in a particle-containing liquid obtained by adding fluorescent dye-containing resin particles to the medium, the rate of change in the backscatter intensity (transmitted light) at the center of the height of the particle-containing liquid left to stand for 24 hours after the addition is not less than −1% based on the particle-containing liquid immediately after the addition.

Claims

exact text as granted — not AI-modified
1 . A medium for storing fluorescent dye-containing resin particles,
 wherein, in a particle-containing liquid obtained by adding fluorescent dye-containing resin particles to said medium, the rate of change in the backscatter intensity (transmitted light) at the center of the height of said particle-containing liquid left to stand for 24 hours after said addition is not less than −1% based on said particle-containing liquid immediately after said addition.   
     
     
         2 . The medium according to  claim 1 , comprising a buffer, a protein and a surfactant. 
     
     
         3 . The medium according to  claim 2 , wherein said surfactant is a nonionic surfactant. 
     
     
         4 . The medium according to  claim 1 , wherein the wavelength of a light irradiated at said center of said height is longer than the particle size of said fluorescent dye-containing resin particles. 
     
     
         5 . The medium according to  claim 1 , wherein said fluorescent dye-containing resin particles are used for pathological staining. 
     
     
         6 . The medium according to  claim 1 , wherein said fluorescent dye-containing resin particles further comprise a reactive functional group. 
     
     
         7 . The medium according to  claim 1 , wherein a resin constituting said fluorescent dye-containing resin particles is a thermosetting resin. 
     
     
         8 . The liquid of  claim 2 , wherein the protein is casein. 
     
     
         9 . The liquid of  claim 2 , wherein the protein comprises 0.6% α-casein, 0.6% β-casein, and 3% BSA. 
     
     
         10 . The liquid of  claim 2 , wherein the protein comprises 10% BSA.

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