US2021369816A1PendingUtilityA1
Formulations of abaloparatide, transdermal patches thereof, and uses thereof
Est. expiryApr 18, 2036(~9.7 yrs left)· nominal 20-yr term from priority
Inventors:Gary HattersleyAlan HarrisJamal SaehEhab HamedKenneth BrownDaniel DohmeierJoan T. MosemanYing ZhangLisa Dick
A61K 33/30A61K 9/703A61K 9/0021A61P 19/10A61K 33/06A61P 19/02A61K 38/29A61K 9/0014A61K 47/10
66
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Claims
Abstract
Disclosed are abaloparatide formulations for transdermal delivery of a therapeutically effective amount of abaloparatide, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.
Claims
exact text as granted — not AI-modified1 . A preparation formulation suitable for coating a transdermal patch wherein said preparation formulation comprises abaloparatide, water and one or more excipients selected from the group consisting of Zn 2+ salts, Mg 2+ salts, Ca 2+ salts, polyethylene glycols and hydroxypropyl beta-cyclodextrins.
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