Contact lens use in the treatment of an ophthalmologic condition

Abstract

The present disclosure relates to the use of contact lenses for treating one or more ophthalmologic conditions. In some embodiments, the contact lenses may be used to treat presbyopia, induced myopia, computer vision syndrome (CVS), insufficient accommodation, or a condition associated with insufficient accommodation. The contact lens may include a number of regions having different geometries (e.g., curvature, width, diameter) depending on the flattest keratonomy of the cornea to achieve a suitable fit. For example, the contact lens may include an optic zone surrounded by an inner peripheral region and an outer peripheral region surrounding the inner peripheral region, each exhibiting varying degrees of curvature. The fitted contact lens may be selected based on a measured sagittal depth and/or eccentricity of the cornea. When fitted, an appropriate amount of fluid may accumulate between the cornea of the eye and the contact lens. In addition, the lens may exhibit a sufficient amount of apical clearance such that when the wearer blinks, the lens moves no more than 1 mm on the eye. Further, the lens and the eye may be mutually structured such that bubbles greater than 0.5 mm in diameter are prevented from forming between the contact lens and the eye. The contact lens may be used in combination with a suitable bioactive agent providing for enhanced visual correction.

1 . A method of fitting a contact lens for an eye of a subject, comprising:
 determining a radius of curvature at the flattest corneal meridian of the eye;   selecting a contact lens having an optic zone with a curvature that varies from a curvature at the flattest corneal meridian of the eye by between approximately 2.0 and approximately 6.0 diopters; and   determining a sagittal depth of the cornea of the eye and selecting a contact lens having an optic zone with a radius of curvature equal to the sagittal depth of the cornea plus a distance of between approximately 0.05 mm and approximately 0.25 mm.   
     
     
         2 . The method of  claim 1 , wherein selecting the contact lens comprises selecting a contact lens having an optic zone with a curvature that is greater than a curvature at the flattest corneal meridian of the eye by between approximately 2.0 and approximately 6.0 diopters. 
     
     
         3 . The method of  claim 1 , wherein selecting the contact lens comprises selecting a contact lens having an optic zone with a curvature that is less than a curvature at the flattest corneal meridian of the eye by between approximately 2.0 and approximately 6.0 diopters. 
     
     
         4 . The method of  claim 1 , wherein selecting a contact lens comprises selecting a contact lens having an optic zone with a curvature that varies from a curvature at the flattest corneal meridian of the eye by between approximately 3.5 and approximately 5.5 diopters. 
     
     
         5 . The method of  claim 1 , wherein selecting a contact lens comprises selecting a contact lens such that, when the contact lens is fit on to the eye, a fluid volume between the cornea of the eye and the contact lens is maintained between approximately 0.05 cubic mm and approximately 0.3 cubic mm. 
     
     
         6 . The method of  claim 1 , wherein selecting a contact lens comprises selecting a contact lens such that, when the contact lens is fit on to the eye, upon blinking of the eye, the contact lens does not move by more than 1 mm. 
     
     
         7 . The method of  claim 1 , wherein selecting a contact lens comprises selecting a contact lens such that, when the contact lens is fit on to the eye, bubbles greater than 0.5 mm in diameter are prevented from forming between the contact lens and the eye. 
     
     
         8 . The method of  claim 1 , further comprising treating an ophthalmologic condition selected from the group consisting of presbyopia, computer vision syndrome (CVS), and insufficient accommodation. 
     
     
         9 . The method of  claim 8 , wherein treating the ophthalmologic condition comprises applying a therapeutic agent between the contact lens and the eye when the contact lens is fit on to the eye. 
     
     
         10 . A method of fitting a contact lens for an eye of a subject, comprising:
 determining a radius of curvature at the flattest corneal meridian of the eye; and   selecting a contact lens having an optic zone with a curvature that varies from a curvature at the flattest corneal meridian of the eye by between approximately 2.0 and approximately 6.0 diopters and such that, when the contact lens is fit on to the eye, a fluid volume between the cornea of the eye and the contact lens is maintained between approximately 0.05 cubic mm and approximately 0.3 cubic mm.   
     
     
         11 . The method of  claim 10 , wherein the fluid volume between the cornea of the eye and the contact lens is a tear volume. 
     
     
         12 . The method of  claim 10 , further comprising determining a sagittal depth of the cornea of the eye and selecting a contact lens having an optic zone with a radius of curvature equal to the sagittal depth of the cornea plus a distance of between approximately 0.05 mm and approximately 0.25 mm. 
     
     
         13 . The method of  claim 10 , wherein selecting a contact lens comprises selecting a contact lens having an optic zone with a curvature that varies from a curvature at the flattest corneal meridian of the eye by between approximately 3.5 and approximately 5.5 diopters. 
     
     
         14 . The method of  claim 10 , wherein selecting a contact lens comprises selecting a contact lens such that, when the contact lens is fit on to the eye, upon blinking of the eye, the contact lens does not move by more than 1 mm. 
     
     
         15 . The method of  claim 10 , wherein selecting a contact lens comprises selecting a contact lens such that, when the contact lens is fit on to the eye, bubbles greater than 0.5 mm in diameter are prevented from forming between the contact lens and the eye. 
     
     
         16 . The method of  claim 10 , further comprising treating an ophthalmologic condition selected from the group consisting of presbyopia, computer vision syndrome (CVS), and insufficient accommodation. 
     
     
         17 . The method of  claim 16 , wherein treating the ophthalmologic condition comprises applying a therapeutic agent between the contact lens and the eye when the contact lens is fit on to the eye. 
     
     
         18 . A method of using a contact lens, comprising:
 placing a contact lens on a cornea of an eye such that, when the contact lens is fit on to the eye, a fluid volume between the cornea of the eye and the contact lens is maintained between approximately 0.05 cubic mm and approximately 0.3 cubic mm, the contact lens comprising:   an optic zone having an optic zone diameter of between 7.0 mm and 9.0 mm and a radius of curvature of between approximately 7.0 mm and approximately 10.0 mm, and an inner peripheral region surrounding the optic zone, wherein inner peripheral region has a radius of curvature of between approximately 0.5 mm and approximately 1.5 mm greater than a radius of curvature of the optic zone.   
     
     
         19 . The method of  claim 18 , wherein the optic zone of the contact lens has a radius of curvature equal to a sagittal depth of the cornea of the eye plus a distance of between approximately 0.05 mm and approximately 0.25 mm. 
     
     
         20 . A method for treating an ophthalmologic condition, the method comprising using the contact lens according to  claim 18  and applying one or more corneal softening agents to the eye of a subject suffering from or likely to suffer from the ophthalmologic condition. 
     
     
         21 - 24 . (canceled)