Polymer-cyclic molecule structure and method for producing the same

Abstract

Provided is a structure including a plurality of pseudo-polyrotaxanes and/or polyrotaxanes each including a chain polymer included in a cavity or cavities of one or more cyclic molecules in a skewered manner, at least part of the plurality of pseudo-polyrotaxanes and/or polyrotaxanes being arranged in series with each other.

1 . A structure comprising a plurality of pseudo-polyrotaxanes and/or polyrotaxanes each including a chain polymer included in a cavity or cavities of one or more cyclic molecules in a skewered manner, at least part of the plurality of pseudo-polyrotaxanes and/or polyrotaxanes being arranged in series with each other. 
     
     
         2 . The structure according to  claim 1 , wherein the chain polymer is a single chain. 
     
     
         3 . The structure according to  claim 1 , wherein the chain polymer is included in the cavities of the three or more cyclic molecules per one chain polymer in a skewered manner. 
     
     
         4 . The structure according to  claim 1 , wherein at least part of the plurality of pseudo-polyrotaxanes and/or polyrotaxanes are arranged in parallel with each other. 
     
     
         5 . The structure according to  claim 1 , further comprising a substance that is bonded to the chain polymer, is bonded to the cyclic molecule, or is held in one of a space between the plurality of pseudo-polyrotaxanes and/or polyrotaxanes, the cavity defined and formed by the one cyclic molecule, and a space defined and formed by the plurality of cyclic molecules. 
     
     
         6 . The structure according to  claim 5 , wherein the substance is at least one selected from the group consisting of a drug, a fluorescent substance, and a chromogenic enzyme. 
     
     
         7 . The structure according to  claim 1 , wherein the chain polymer has a length of from 1 nm to 2,000 nm. 
     
     
         8 . The structure according to  claim 1 , wherein the chain polymer includes a moiety formed of one of polyethylene glycol (PEG) or polypropylene glycol (PPG). 
     
     
         9 . The structure according to  claim 1 , wherein the cyclic molecule is at least one selected from the group consisting of a cyclodextrin, a crown ether, a pillararene, a calixarene, a cyclophane, and derivatives thereof. 
     
     
         10 . The structure according to  claim 1 , wherein the structure has arranged therein at least one through-hole penetrating the structure and occupying a space larger than a volume occupied by the one pseudo-polyrotaxane and/or polyrotaxane. 
     
     
         11 . The structure according to  claim 1 , wherein the structure is any one of the following (a) to (c):
 (a) a rod-shaped structure in which the chain polymer has a weight-average molecular weight of from 200 to 10,000;   (b) a cube-shaped structure in which the chain polymer has a weight-average molecular weight of from 1,000 to 20,000; and   (c) a sheet-shaped structure in which the chain polymer has a weight-average molecular weight of from 2,000 to 200,000.   
     
     
         12 . A method of producing a structure including a plurality of pseudo-polyrotaxanes and/or polyrotaxanes each including a chain polymer included in a cavity or cavities of one or more cyclic molecules in a skewered manner, the method comprising causing the plurality of pseudo-polyrotaxanes and/or polyrotaxanes each including the chain polymer having both ends housed in a column formed of the plurality of cyclic molecules to interact with each other to arrange at least part of the plurality of pseudo-polyrotaxanes and/or polyrotaxanes in series with each other.