Composition of nutrition supplementation for nutritional deficiencies and method of use therefore

Abstract

A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a nutritional supplements composition for treating a subject with complications resulting from sickle cell anemia. The method comprises administering to a subject an effective amount of the nutritional supplement.

What is claimed is: 
     
         1 . A method for treating conditions associated with abnormally slow energy metabolism or high energy requirement, comprising:
 administering to a subject in need of such treatment a daily nutritional supplement having total calories of about 700-980 kcal, wherein about 10-20% of the total calories are derived from protein, about 25-40% of the total calories are derived from fat, and about 45-65% of the total calories are derived from carbohydrate.   
     
     
         2 . The method of  claim 1 , wherein the conditions associated with abnormally slow energy metabolism include malnutrition, anorexia, cancers, AIDS and aging. 
     
     
         3 . The method of  claim 1 , wherein the conditions associated with high energy requirement include sickle cell anemia, pregnancy, lactation, growth, exercise, infectious diseases and recovery from surgical and other injuries. 
     
     
         4 . The method of  claim 3 , wherein the condition associated with high energy requirement is sickle cell anemia. 
     
     
         5 . The method of  claim 1 , wherein the nutritional supplement is administered orally in the form of a snack. 
     
     
         6 . The method of  claim 5 , wherein the nutritional supplement is administered orally as the last snack before sleeping. 
     
     
         7 . The method of  claim 5 , wherein the nutritional supplement is administered as snacks after each meal. 
     
     
         8 . A nutritional supplement to normal diet for treating conditions associated with abnormally slow energy metabolism or high energy requirement, comprising:
 protein in an amount that provides about 10-20% of the total calories;   fat in an amount that provides about 25-40% of the total calories; and   carbohydrate that provides about 45-65% of the total calories.   
     
     
         9 . The nutritional supplement of  claim 8 , wherein the nutritional supplement comprises:
 protein in an amount that provides about 14% of the total calories;   fat in an amount that provides about 32% of the total calories; and   carbohydrate that provides about 54% of the total calories.   
     
     
         10 . The nutritional supplement of  claim 8 , wherein the nutritional supplement has a total calorie of about 700-980 kcal. 
     
     
         11 . The nutritional supplement of  claim 10 , wherein the nutritional supplement comprises about 24-34 grams of protein; about 25-35 grams of fat; and about 96-135 grams of carbohydrate. 
     
     
         12 . The nutritional supplement of  claim 8 , wherein the nutritional supplement further comprises at least one food grade amino acid selected from the group consisting of arginine, histidine, leucine, valine, cysteine and glutamine. 
     
     
         13 . The nutritional supplement of  claim 12 , wherein the nutritional supplement comprises arginine, histidine, leucine, valine, cysteine and glutamine, and wherein each amino acid is provided at a per diem dose range of 8-14 mg/kg body weight/day. 
     
     
         14 . The nutritional supplement of  claim 12 , wherein the nutritional supplement comprises arginine, histidine, leucine, valine, cysteine and glutamine, and wherein each amino acid is provided at a per diem dose range of 22-44 mg/kg body weight/day. 
     
     
         15 . The nutritional supplement of  claim 12 , wherein the nutritional supplement further comprises S-allyl cysteines, S-allyhmercapto cysteine and fructosyl arginine. 
     
     
         16 . The nutritional supplement of  claim 12 , wherein the nutritional supplement further comprises a garlic extract. 
     
     
         17 . The nutritional supplement of  claim 8 , wherein the nutritional supplement further comprises one or more antioxidants. 
     
     
         18 . The nutritional supplement of  claim 17 , wherein the one or more antioxidants is selected from the group consisting of Vitamin A, Vitamin C, Vitamin E, β-carotene and selenium. 
     
     
         19 . The nutritional supplement of  claim 17 , wherein the one or more antioxidants comprise Vitamin C and Vitamin E. 
     
     
         20 . The nutritional supplement of  claim 8 , further comprising one or more components selected from the group consisting of: Vitamin A 8,250-250,000 I.U., Vitamin B-1 25-1000 mg, Vitamin B-2 25-1000 mg, Vitamin B-6 25-1000 mg, Vitamin B-12 25-1000 mcg, Vitamin C 25-1000 mg, Vitamin D 100-4000 I.U., Vitamin E 25-1000 I.U., Niacinamide 25-1000 mg, Paraaminobenzoic acid (PABA) 25-1000 mg, Pantothenic Acid 25-1000 mg, Choline Bitartrate 25-1000 mg, Inositol 25-1000 mg, Rutin 8.25-250 mg, Citrus Bioflavonoid Complex 8.25-250 mg, Betaine Hydrochloride 8.25-250 mg, Hesperidin Complex 1.25-50 mg, Folic Acid 100-4000 mcg, Biotin 25-1000 mcg, Calcium 10-400 mg, Iron 8.25-250 mg, Magnesium 5-100 mg, Zinc 5-100 mg, Potassium 3.75-150 mg, Manganese 1.5-60 mg, Iodine 37,5-1500 meg, Chromium 3.75-150 mcg, and Selenium 2.5-100 mcg. 
     
     
         21 . The nutritional supplement of  claim 20 , further comprising one or more component selected from the group consisting of L-lysine-L-phenylalanine, L-lysine-L-tyrosine, L-histidine-L-lysine-L-tyrosine-L-histidine, and salts thereof at a dose range of 10-150 mg/kg/day. 
     
     
         22 . The nutritional supplement of  claim 20 , further comprising L-lysine-L-phenylalanine or salts thereof at a dose range of 20-80 mg/kg/day. 
     
     
         23 . The nutritional supplement of  claim 8 , further comprising thiocyanates in an amount of 100-500 mg. 
     
     
         24 . The nutritional supplement of  claim 23 , wherein the thiocyanate is mixed with Vitamin B6 at a weight ratio of about 20:1. 
     
     
         25 . The nutritional supplement of  claim 8 , wherein the nutritional supplement is formulated in a ready-to-dispense single-dose form designed for complete consumption as a snack. 
     
     
         26 . The nutritional supplement of  claim 8 , wherein the nutritional supplement is formulated in a ready-to-dispense three-dose form designed as a snack after each meal. 
     
     
         27 . The nutritional supplement of  claim 8 , wherein the nutritional supplement is formulated for complete consumption as a two-pack snack to be taken in the morning and evening.