US2021236860A1PendingUtilityA1

Selective removal of cells having accumulated agents

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Assignee: SIWA CORPPriority: Nov 22, 2010Filed: Feb 16, 2021Published: Aug 5, 2021
Est. expiryNov 22, 2030(~4.3 yrs left)· nominal 20-yr term from priority
Inventors:Lewis S. Gruber
C12N 13/00C12N 5/0093A61B 2017/320069A61P 35/00A61B 8/00A61N 7/00
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Claims

Abstract

A method of treating a condition associate with accumulation of an agent in cells in a patient includes exposing the cells to ultrasound, to selectively kill or induce apoptosis in the cells. The cells include the accumulated agent.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of treating a condition associate with accumulation of an agent in cells in a patient, comprising exposing the cells comprising the accumulated agent to ultrasound, to selectively kill or induce apoptosis in the cells. 
     
     
         2 . The method of  claim 1 , wherein the cells are not AGE-modified cells. 
     
     
         3 . The method of  claim 1 , wherein the agent is selected from the group consisting of proteins, lipids, bacteria, viruses and parasites. 
     
     
         4 . The method of  claim 1 , wherein the cells are not tumor cells. 
     
     
         5 . The method of  claim 1 , wherein the cells are not cancerous. 
     
     
         6 . The method of  claim 1 , wherein the agent is selected from the group consisting of bacteria, viruses and parasites. 
     
     
         7 . The method of  claim 1 , wherein the agent is selected from the group consisting of proteins and lipids. 
     
     
         8 . The method of  claim 1 , wherein the cells are infected with a disease-causing organism. 
     
     
         9 . The method of  claim 8 , wherein the disease-causing organism is selected from the group consisting of bacteria, viruses and parasites. 
     
     
         10 . The method of  claim 1 , wherein the cells are blood cells. 
     
     
         11 . The method of  claim 10 , wherein the cells red blood cells. 
     
     
         12 . The method of  claim 10 , wherein the cells are white blood cells. 
     
     
         13 . The method of  claim 1 , further comprising testing the cells, to determine ultrasound frequency and power to selectively kill or induce apoptosis in the cells. 
     
     
         14 . The method of  claim 13 , wherein the testing comprises testing cells taken from the patient. 
     
     
         15 . The method of  claim 1 , wherein exposing the cells comprises exposing the cells to a plurality of ultrasound treatments. 
     
     
         16 . The method of  claim 1 , wherein the patient is infected with a disease-causing organism. 
     
     
         17 . The method of  claim 16 , wherein the disease-causing organism is selected from the group consisting of bacteria, viruses and parasites. 
     
     
         18 . The method of  claim 16 , wherein the agent is selected from the group consisting of proteins and lipids. 
     
     
         19 . The method of  claim 1 , wherein the condition is a chronic disease. 
     
     
         20 . A method of removing cells from a sample, comprising:
 exposing the sample to ultrasound, to selectively kill or induce apoptosis in the cells,   wherein the cells comprise an accumulated agent.   
     
     
         21 . The method of  claim 20 , wherein the sample is obtained from a patient.

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