Blood Storage Containers Made of Polyvinyl Chloride and Mixed Plasticizers

Abstract

Flexible, blood storage containers are disclosed. The blood storage containers are made of polyvinyl chloride and a mixture of at least two plasticizers in selected ratios.

1 . A flexible blood storage container comprising a pair of walls defining an interior chamber and at least one access port, said container made of a polymeric material comprising polyvinyl chloride and a mixture of least two extractable plasticizers comprising at least 78% 1, 2 cyclohexanedicarboxyylic acid diisononyl ester and up to 22% acetyl tri-n-butyl citrate of the at least two plasticizer mixture. 
     
     
         2 . The flexible storage container of  claim 1  wherein said mixture of extractable plasticizers comprises at least 85% 1, 2 cyclohexanedicarboxyylic acid diisononyyl ester and up to 15% acetyl tri-n-butyl citrate. 
     
     
         3 . The flexible storage container of  claim 1  wherein said mixture of extractable plasticizers comprises at least 90% 1, 2 cyclohexanedicarboxyylic acid diisononyl ester and up to 10% acetyl tri-n-butyl citrate. 
     
     
         4 . The flexible storage container of  claim 1  wherein said mixture of extractable plasticizers comprises at least 95% 1, 2 cyclohexanedicarboxyylic acid diisononyl ester and up to 5% acetyl tri-n-butyl citrate. 
     
     
         5 . The flexible blood storage container of  claim 1  wherein said polymeric material further comprises a stabilizer comprising epoxidized vegetable oil. 
     
     
         6 . The flexible blood storage container of  claim 1  wherein said polymeric material further comprises a co-stabilizer comprising a metal stearate. 
     
     
         7 . A flexible blood storage container comprising a pair of walls defining an interior chamber and at least one access port, said container made of a polymeric material comprising polyvinyl chloride and at mixture of least two extractable plasticizers comprising at least 75% di-2-ethylhexyl terephthalate ester and up to 25% acetyl tri-n-butyl citrate of the plasticizer mixture. 
     
     
         8 . The flexible blood storage container of  claim 7  wherein said mixture of extractable plasticizers comprises at least 80% di-2-ethylhexyl terephthalate ester and up to 20% acetyl tri-n-butyl citrate. 
     
     
         9 . The flexible blood storage container of  claim 7  wherein said mixture of plasticizers comprises at least 85% di-ethylhexyl terephthalate ester and up to 15% acetyl tri-n-butyl citrate. 
     
     
         10 . The flexible blood storage container of  claim 7  wherein said mixture of plasticizers comprises at least 90% di-ethyl hexyl terephthalate ester and up to 10% acetyl tri-n-butyl citrate. 
     
     
         11 . The flexible, blood storage container of  claim 7  wherein said mixture of plasticizers comprises at least 95% di-ethyl hexyl terephthalate ester and up to 5% acetyl tri-n-butyl citrate. 
     
     
         12 . The flexible blood storage container of  claim 7  wherein said polymeric material further comprises a stabilizer comprising epoxidized vegetable oil. 
     
     
         13 . The flexible blood storage container of  claim 7  wherein said polymeric material further comprises a co-stabilizer comprising a metal stearate. 
     
     
         14 . A flexible blood storage container comprising a pair of walls defining an interior chamber and at least one access port, said container made of a polymeric material comprising polyvinyl chloride and at mixture of least two extractable plasticizers comprising 1, 2 cyclohexanedicarboxyylic acid diisononyl ester and di-2-ethylhexyl terephthalate ester. 
     
     
         15 . The flexible blood storage container of  claim 14  wherein said polymeric material further comprises a stabilizer comprising epoxidized vegetable oil. 
     
     
         16 . The flexible blood storage container of  claim 14  wherein said polymeric material further comprises a co-stabilizer comprising a metal stearate. 
     
     
         17 . The flexible blood storage container comprising a pair of walls defining an interior chamber and at least one access port, said container made of a polymeric material comprising polyvinyl chloride and at mixture of least two extractable plasticizers comprising di-2-ethylhexyl terephthalate ester and acetyl tri-n-hexyl citrate. 
     
     
         18 . The flexible blood storage container of  claim 17  wherein said mixture of plasticizers comprises at least 90% di-ethyl hexyl terephthalate ester and up to 10% acetyl tri-n-hexyl citrate. 
     
     
         19 . The flexible blood storage container of  claim 17  wherein said polymeric material further comprises a stabilizer comprising epoxidized vegetable oil. 
     
     
         20 . The flexible blood storage container of  claim 17  wherein said polymeric material further comprises a co-stabilizer comprising a metal stearate. 
     
     
         21 . The flexible blood storage container comprising a pair of walls defining an interior chamber and at least one access port, said container made of a polymeric material comprising polyvinyl chloride and at mixture of least two extractable plasticizers comprising di-2-ethylhexyl terephthalate ester and butyl tri-n-hexyl citrate. 
     
     
         22 . The flexible blood storage container of  claim 20  wherein said polymeric material further comprises a stabilizer comprising epoxidized vegetable oil. 
     
     
         23 . The flexible blood storage container of  claim 20  wherein said polymeric material further comprises a co-stabilizer comprising a metal stearate. 
     
     
         24 . The flexible, blood storage container of  claim 1  wherein at least one of said pair of walls comprises said polymeric material.