Lactic acid bacteria capable of controlling blood sugar and use thereof

Abstract

A Lactobacillus species strain isolated from kimchi or human feces is described. The particular bacillus species strain described is highly safe by being isolated from kimchi or human feces and has various functionalities, such as excellent blood sugar control activity, anti-obesity activity, blood cholesterol-lowering activity, blood neutral lipid-lowering activity, arteriosclerosis-inhibiting activity or inflammation-inhibiting activity. Accordingly, the particular bacillus species strain described can be used as a useful food and drug material for preventing, alleviating or treating a metabolic syndrome including diabetes, obesity, fatty liver, glycosuria, hyperlipidemia, cardiovascular disease, hypertension, arteriosclerosis and/or diabetes, an inflammatory disease, and the like.

1 - 5 . (canceled) 
     
     
         6 . A method for lowering blood sugar comprising administering to a subject in need thereof an effective amount of a composition comprising  Lactobacillus sakei  OK67 (accession number: KCCM 11670P) strain, a culture thereof, a lysate thereof or an extract thereof as an active ingredient. 
     
     
         7 . (canceled) 
     
     
         8 . A method for preventing, alleviating or treating diabetes, obesity ef metabolic syndrome or an inflammatory disease comprising administering to a subject in need thereof an effective amount of a composition comprising  Lactobacillus sakei  OK67 (accession number: KCCM 11670P) strain, a culture thereof, a lysate thereof or an extract thereof as an active ingredient. 
     
     
         9 . The method according to  claim 8 , wherein the metabolic syndrome is a disease in which one or more diseases selected from the group consisting of diabetes and obesity occur simultaneously with one or more diseases selected from the group consisting of fatty liver, hyperlipidemia, cardiovascular disease, hypertension and arteriosclerosis. 
     
     
         10 - 11 . (canceled) 
     
     
         12 . A method for regulating or enhancing immunity comprising administering to a subject in need thereof an effective amount of a composition comprising  Lactobacillus sakei  OK67 (accession number: KCCM 11670P) strain, a culture thereof, a lysate thereof or an extract thereof as an active ingredient. 
     
     
         13 . (canceled) 
     
     
         14 . The method according to  claim 8 , wherein the inflammatory disease is arthritis or colitis. 
     
     
         15 . (canceled) 
     
     
         16 . The method according to  claim 8 , wherein the metabolic syndrome is a disease in which one or more diseases selected from the group consisting of diabetes and obesity occur simultaneously with fatty liver. 
     
     
         17 . The method according to  claim 8 , wherein the composition is a pharmaceutical composition or a food composition.