Aneurysm method and system

Abstract

A vaso-occlusive device is disclosed herein having a delivery configuration when restrained within a delivery catheter and a deployed configuration when released from the delivery catheter into an aneurysmal sac. The vaso-occlusive device includes a tubular structure and an elongated embolic element. The tubular structure is configured to form at least two nested sacks within the aneurysm, thereby creating a multi-layer scaffolding within the aneurysm sac. The elongate embolic element is coupled to proximal end of the tubular structure and is configured to fill an interior region of the multi-layer scaffolding when deployed into the aneurysmal sac. At least one of the two nested sacks can be inverted upon deployment. The tubular structure can include a tubular braided mesh.

1 . A vaso-occlusive device having a delivery configuration when restrained within a delivery catheter and a deployed configuration when released from the delivery catheter into an aneurysmal sac, the vaso-occlusive device comprising:
 a tubular structure, comprising:
 a distal portion configured to form a first sack within the aneurysmal sac when distally deployed from the delivery catheter into the aneurysmal sac, 
 a proximal portion configured to form a second sack within the first sack when distally deployed from the delivery catheter, thereby creating multi-layer scaffolding within the aneurysmal sac; and 
   an elongate embolic element coupled to proximal end of the tubular structure, wherein the elongate embolic element is configured to fill an interior region of the multi-layer scaffolding when distally deployed from the delivery catheter into the aneurysmal sac.   
     
     
         2 . The vaso-occlusive device of  claim 1 , wherein the tubular structure comprises a tubular braided mesh. 
     
     
         3 . The vaso-occlusive device of  claim 1 , wherein the elongate embolic element comprises a braided ribbon. 
     
     
         4 . The vaso-occlusive device of  claim 1 , wherein the elongate embolic element comprises an embolic coil. 
     
     
         5 . The vaso-occlusive device of  claim 1 , wherein at least one of the distal portion and the proximal portion is configured to invert upon movement of the vaso-occlusive device from the delivery configuration to the deployed configuration. 
     
     
         6 . The vaso-occlusive device of  claim 5 , wherein the tubular structure further comprises an inflection region between the distal portion and the proximal portion, the inflection region configured to urge the inversion of the proximal portion and/or urge the inversion of the distal portion. 
     
     
         7 . The vaso-occlusive device of  claim 6 , wherein the inflection region is configured for urging the inversion of the proximal portion and/or the distal portion while the vaso-occlusion device moves from the delivery configuration to the deployed configuration in free-space. 
     
     
         8 . The vaso-occlusive device of  claim 1 , wherein each of the distal portion and the proximal portion is configured for self-expanding into a spherical, oblong, or saddle shape. 
     
     
         9 . The vaso-occlusive device of  claim 1 , wherein the distal portion comprises a non-expanding terminal end. 
     
     
         10 . An implant configured to traverse vasculature within a delivery catheter and move from a delivery configuration with restrained by the delivery catheter to a deployed configuration within a spherical cavity, the implant comprising:
 an expandable tubular braid comprising a first portion configured to form a first sack conformal to walls of the spherical cavity and a second portion configured to form a second sack within the first sack when the implant moves from the delivery configuration to the deployed configuration; and   an elongate embolic element coupled to the tubular braid and configured to be positioned within the first sack and the second sack when the implant moves from the delivery configuration to the deployed configuration.   
     
     
         11 . The implant of  claim 10 , wherein the elongate embolic element comprises a braided ribbon. 
     
     
         12 . The implant of  claim 10 , wherein the elongate embolic element comprises an embolic coil. 
     
     
         13 . The implant of  claim 10 , wherein at least one of the first portion and the second portion is configured to invert upon movement of the implant from the delivery configuration to the deployed configuration. 
     
     
         14 . A method of treating an aneurysm in a patient, the method comprising:
 distally advancing a vaso-occlusive device in a delivery configuration through a delivery catheter to an aneurysm neck, the vaso-occlusive device comprising a tubular structure and an elongated embolic element coupled to a proximal end of the tubular structure;   deploying a distal portion of the tubular structure from a distal end of the delivery catheter into a sac of the aneurysm;   expanding the distal portion of the tubular structure, thereby creating a single-layer scaffolding that lines a wall of the aneurysm sac;   deploying a proximal portion of the tubular structure from the distal end of the delivery catheter;   expanding the proximal portion of the tubular structure within the expanded distal portion of the tubular structure, thereby creating a multi-layer scaffolding that lines the wall of the aneurysm sac; and   positioning the elongated embolic element within the multi-layer scaffolding.   
     
     
         15 . The method of  claim 14 , wherein the tubular structure comprises a tubular braided mesh. 
     
     
         16 . The method of  claim 14 , wherein the elongate embolic element comprises an embolization coil and/or a braided ribbon. 
     
     
         17 . The method of  claim 14 , further comprising:
 inverting at least of the distal portion and the proximal portion upon deployment of the tubular structure from the distal end of the delivery catheter.   
     
     
         18 . The method of  claim 17 , wherein the tubular structure further comprises an inflection region between the distal portion and the proximal portion, the inflection region configured to urge the inversion of the proximal portion and/or urge the inversion of the distal portion. 
     
     
         19 . The method of  claim 18 , wherein inversion of the tubular structure at the inflection region is initiated absent an application of an opposing proximal force on the tubular structure by a dome of the aneurysmal sac. 
     
     
         20 . The method of  claim 14 , further comprising:
 expanding each of the distal portion and the proximal portion respectively into a spherical, oblong, or saddle shape.