Multi-layer osteoinductive, osteogenic, and osteoconductive carrier

Abstract

A method of making a multi-layer osteogenic carrier device for use in a vertebral column of a patient, comprising producing an elongated tubular structure, the elongated tubular structure comprising a closed end and an open end, wherein the open end is adapted for introducing an osteoinductive, osteogenic, and/or osteoconductive substance; cutting the elongated tubular structure to a certain length; introducing the osteoinductive, osteogenic, and/or osteoconductive substance into the open end of the elongated tubular structure; and closing the open end of the elongated tubular structure to form the multi-layer osteogenic carrier device.

What is claimed is: 
     
         1 . A method of making a multi-layer osteogenic carrier device for use in a vertebral column of a patient, comprising:
 producing an elongated tubular structure, the elongated tubular structure comprising a closed end and an open end,   wherein the open end is adapted for introducing an osteoinductive, osteogenic, and/or osteoconductive substance;   cutting the elongated tubular structure to a certain length;   introducing the osteoinductive, osteogenic, and/or osteoconductive substance into the open end of the elongated tubular structure; and   closing the open end of the elongated tubular structure to form the multi-layer osteogenic carrier device.   
     
     
         2 . The method of  claim 1 , wherein a porous substance is introduced into the elongated tubular structure along with the osteoinductive, osteogenic, and/or osteoconductive substance. 
     
     
         3 . The method of  claim 1 , wherein the elongated tubular structure is produced in a predetermined length and/or size and/or thickness. 
     
     
         4 . The method of  claim 1 , wherein the step of closing the open end of the elongated tubular structure comprises sewing, clipping, and/or sealing. 
     
     
         5 . The method of  claim 3 , wherein the predetermined length and/or diameter of the elongated tubular structure is determined by the introduced substance. 
     
     
         6 . The method of  claim 1 , wherein the multi-layer osteogenic carrier device further comprises at least one rod, at least one rod clip, and/or at least one fastener. 
     
     
         7 . The method of  claim 1 , further comprising freezing or treating the multi-layer osteogenic carrier device. 
     
     
         8 . The method of  claim 7 , wherein in use, the multi-layer osteogenic carrier device is produced in a predetermined length and/or diameter and/or thickness and multiple multi-layer osteogenic carrier devices are combined for use in the patient's vertebral column. 
     
     
         9 . The method of  claim 7 , wherein in use, the multi-layer osteogenic carrier device is produced in a predetermined length and/or diameter and is cut for use in the patient's vertebral column. 
     
     
         10 . The method of  claim 1 , wherein the elongated tubular material is adherent to bone and/or tissue. 
     
     
         11 . The method of  claim 1 , wherein a support layer is applied to the exterior of the multi-layer osteogenic device. 
     
     
         12 . A method of making a multi-layer osteogenic carrier device for use in a vertebral column of a patient, comprising:
 producing an elongated tubular structure, the elongated tubular structure comprising two closed ends and a port or opening,   wherein the port or opening is adapted for introducing an osteoinductive, osteogenic, and/or osteoconductive substance;   introducing the osteoinductive, osteogenic, and/or osteoconductive substance into the port or opening of the elongated tubular structure; and   closing the port or opening of the elongated tubular structure to form the multi-layer osteogenic carrier device.   
     
     
         13 . The method of  claim 12 , wherein a porous substance is introduced into the elongated tubular structure along with the osteoinductive, osteogenic, and/or osteoconductive substance. 
     
     
         14 . The method of  claim 12 , wherein the elongated tubular structure is produced in a predetermined length and/or size and/or thickness. 
     
     
         15 . The method of  claim 12 , wherein the step of closing the port or opening of the elongated tubular structure comprises sewing and/or sealing. 
     
     
         16 . The method of  claim 12 , wherein the multi-layer osteogenic carrier device further comprises at least one rod, at least one rod clip, and/or at least one fastener. 
     
     
         17 . The method of  claim 12 , further comprising freezing or treating the multi-layer osteogenic carrier device. 
     
     
         18 . The method of  claim 17 , wherein in use, the multi-layer osteogenic carrier device is produced in a predetermined length and/or diameter and/or thickness and multiple multi-layer osteogenic carrier devices are combined for use in the patient's vertebral column. 
     
     
         19 . The method of  claim 12 , wherein the elongated tubular material is adherent to bone and/or tissue. 
     
     
         20 . The method of  claim 12 , wherein a support layer is applied to the exterior of the multi-layer osteogenic device.