Therapeutic agent for dry eye characterized by being applied to eye of dry eye patient wearing soft contact lens

Abstract

An ophthalmic solution, which comprises diquafosol tetrasodium salt and is free from benzalkonium chloride, treats onset and/or exacerbation of dry eye symptom caused by wearing soft contact lenses.

1 . A therapeutic agent for dry eye characterized by being applied to an eye of a dry eye patient wearing soft contact lens, which comprises diquafosol or a salt thereof as an active ingredient and does not comprise benzalkonium chloride. 
     
     
         2 . The therapeutic agent according to  claim 1 , which is contained in a unit-dose type container. 
     
     
         3 . The therapeutic agent according to  claim 1 , which is contained in a multi-dose type container. 
     
     
         4 . The therapeutic agent according to  claim 3 , which comprises a preservative other than benzalkonium chloride. 
     
     
         5 . The therapeutic agent according to  claim 4 , wherein the preservative other than benzalkonium chloride is at least one selected from the group consisting of chlorhexidines, borates, chlorites, parabenes, sorbates, chlorobutanol and benzethonium chloride. 
     
     
         6 . The therapeutic agent according to  claim 4 , wherein the preservative other than benzalkonium chloride is chlorhexidines. 
     
     
         7 . The therapeutic agent according to  claim 1 , wherein a concentration of the diquafosol or a salt thereof is 0.5 to 5% (w/v). 
     
     
         8 . The therapeutic agent according to  claim 1 , wherein a concentration of the diquafosol or a salt thereof is 3% (w/v). 
     
     
         9 . The therapeutic agent according to  claim 1 , wherein the dry eye is caused by wearing contact lenses. 
     
     
         10 . An ophthalmic solution for improving tear film stability, characterized by being applied to an eye wearing a soft contact lens, which comprises diquafosol or a salt thereof as an active ingredient and does not comprise benzalkonium chloride. 
     
     
         11 . An ophthalmic solution for treating eye dryness or eye discomfort caused by wearing the soft contact lens, characterized by being applied to an eye wearing a soft contact lens, which comprises diquafosol or a salt thereof as an active ingredient and does not comprise benzalkonium chloride.