US2021128453A1PendingUtilityA1

Co-enzyme q10 formulations and methods of use

Assignee: UNIV MIAMIPriority: Jan 22, 2004Filed: Jun 12, 2020Published: May 6, 2021
Est. expiryJan 22, 2024(expired)· nominal 20-yr term from priority
A61K 36/53A61K 31/351A61K 9/06A61K 47/24A61P 35/04G01N 33/5079A61P 35/02A61K 31/282A61K 31/122A61K 9/0014A61P 35/00A61K 45/06A61P 29/00A61K 31/337A61P 17/00A61P 43/00A61K 38/43G01N 33/58A61P 9/00A61P 9/10
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Claims

Abstract

Topical formulations of CoQ10 reduce the rate of tumor growth in an animcal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing animals with a topical formulation of CoQ10 was shown to dramatically reduce the rate of tumor growth in the animals.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 - 37 . (canceled) 
     
     
         38 . A method of treating a cancer in a subject in need thereof, comprising intravenously administering to the subject having a cancer a composition comprising 0.01% to 30% w/w of Coenzyme Q10 in an amount effective and for a sufficient time to slow the growth of the cancer, thereby treating the cancer in the subject.

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