Aspiration systems and devices

Abstract

Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

1 . (canceled) 
     
     
         2 . A system for facilitating aspiration of material within a body, the system comprising:
 a catheter comprising:
 a lumen; and 
 a variably slotted hypotube comprising a plurality of interspersed cut patterns, 
 wherein the hypotube is configured to inhibit collapse of the lumen during application of negative suction applied through the lumen; and 
   an automated negative suction device comprising a vacuum pump configurable to generate suction patterns,   wherein at least one suction pattern of the suction patterns comprises a plurality of intensity levels, and   wherein the plurality of intensity levels comprises a first intensity level and a second intensity level.   
     
     
         3 . The system of  claim 2 , wherein the automated negative suction device comprises power electronics configured to control at least one of an intensity or a duration of negative suction pressure of the suction patterns. 
     
     
         4 . The system of  claim 3 , wherein the power electronics comprise a customized integrated circuit board or an integrated chip. 
     
     
         5 . The system of  claim 4 , wherein at least some of the suction patterns are stored in the power electronics. 
     
     
         6 . The system of  claim 2 , wherein suction pressure of the first intensity level is between −551 and −769 mm Hg, and wherein suction pressure of the second intensity level is between −100 and −350 mm Hg. 
     
     
         7 . The system of  claim 2 , wherein the suction patterns comprise repetitive cycles. 
     
     
         8 . The system of  claim 2 , wherein the catheter is selected from the group consisting of: a microcatheter, a distal access microcatheter, a guide catheter, and a balloon catheter. 
     
     
         9 . A system for facilitating aspiration of material within a body, the system comprising:
 a suction device configured to generate a plurality of suction patterns;   wherein at least one suction pattern of the plurality of suction patterns comprises a plurality of intensity levels,   wherein the plurality of intensity levels comprises a first intensity level and a second intensity level.   
     
     
         10 . The system of  claim 9 , wherein the at least one suction pattern comprises a repetitive cycle of the first intensity level having a first negative pressure and the second intensity level having a second negative pressure different than the first negative pressure. 
     
     
         11 . The system of  claim 9 :
 wherein the suction device is an automated negative suction device comprising power electronics configured to control at least one of an intensity or a duration of negative suction pressure of the plurality of suction patterns,   wherein the power electronics comprise a customized integrated circuit board or an integrated chip, and   wherein at least some of the plurality of suction patterns are stored in the power electronics.   
     
     
         12 . The system of  claim 9 , wherein suction pressure of the first intensity level is between −551 and −769 mm Hg, and wherein suction pressure of the second intensity level is between −100 and −350 mm Hg. 
     
     
         13 . The system of  claim 9 , wherein suction pressure of the first intensity level is between −551 and −769 mm Hg, and wherein suction pressure of the second intensity level is between −351 and −550 mm Hg. 
     
     
         14 . The system of  claim 9 , wherein the at least one suction pattern comprises a pause duration wherein suction is paused. 
     
     
         15 . The system of  claim 9 , wherein the at least one suction pattern comprises pauses between the plurality of intensity levels. 
     
     
         16 . A system for facilitating aspiration of material within a body, the system comprising:
 an automated negative suction device comprising a vacuum pump configurable to generate suction patterns, wherein at least one of the suction patterns comprises a plurality of suction intensity levels; and   a catheter comprising:
 a variably slotted hypotube comprising a plurality of interspersed cut patterns; and 
 a lumen. 
   
     
     
         17 . The system of  claim 16 :
 wherein the hypotube is configured to inhibit collapse of the lumen during application of negative suction applied through the lumen,   wherein the catheter has a wall thickness between 0.02 mm and 1 mm, and   wherein the catheter has a length between 80 cm and 150 cm.   
     
     
         18 . The system of  claim 17 , wherein the catheter further comprises a polymer having variable braiding parameters, and wherein a durometer of the polymer changes along a length of the catheter. 
     
     
         19 . The system of  claim 16 , wherein the lumen comprises a gradual tapering of inner diameter from a proximal end to a distal end of the catheter. 
     
     
         20 . The system of  claim 16 , wherein the lumen has a uniform diameter along the length of the catheter. 
     
     
         21 . The system of  claim 16 , wherein the catheter is selected from the group consisting of: a microcatheter, a distal access microcatheter, a guide catheter, and a balloon catheter.