Regimens for immunisation with meningococcal conjugates

Abstract

Multivalent meningococcal conjugate vaccines are administered according to a schedule in which a first dose is administered to a patient aged between 0 and 12 months, and a second dose is administered to the patient aged between 12 and 24 months.

1 . A kit comprising: (a) a multivalent meningococcal capsular saccharide-carrier protein conjugate vaccine; and (b) instructions for administering the vaccine according to a schedule that includes: (a) first administering the vaccine to a patient when said patient is about 6 months of age; and (b) then administering the vaccine to the patient when said patient is about 12 months of age, wherein the multivalent meningococcal capsular saccharide-carrier protein conjugate vaccine includes capsular saccharide-carrier protein conjugates of at least meningococcal serogroups A, C, W135 and Y. 
     
     
         2 . The kit of  claim 1 , wherein the carrier protein is selected from diphtheria toxoid and CRM197. 
     
     
         3 . The kit of  claim 1 , wherein the multivalent meningococcal capsular saccharide-carrier protein conjugate vaccine is unadjuvanted. 
     
     
         4 . The kit of  claim 1 , wherein the multivalent meningococcal capsular saccharide-carrier protein conjugate vaccine is adjuvanted. 
     
     
         5 . The kit of  claim 1 , wherein the schedule includes: (a) first administering the vaccine to a patient when said patient is 6 months of age. 
     
     
         6 . The kit of  claim 1 , wherein the schedule includes: (b) administering the vaccine to the patient when said patient is about 12 months of age. 
     
     
         7 . The kit of  claim 1 , wherein the schedule includes: (a) first administering the vaccine to a patient when said patient is 6 months of age; and (b) then administering the vaccine to the patient when said patient is 12 months of age.