Pathogenic control compositions and methods

Abstract

Provided herein are compositions, systems, and methods for treating plant, aquatic, and/or livestock pathogens. More specifically, the present disclosure relates to activated compositions having metal nanoparticles and/or one or more organic acids for the treatment of harmful plant, aquaculture, or livestock pathogens, and also relates to methods of making and using the compositions.

What is claimed is: 
     
         1 . A system for making a composition comprising one or more metal nanoparticles and one or more organic acids, wherein the system comprises:
 one or more activation chambers; and   an energy source.   
     
     
         2 . The system of  claim 1 , wherein the energy source comprises a sonicator, a laser, an electron gun, or a thermal energy source. 
     
     
         3 . The system of  claim 1 , wherein the one or more activation chambers are configured to sonicate the composition at a frequency of about 20 kHz for a period of about 20 minutes to generate a monodisperse matrix fluid. 
     
     
         4 . The system of  claim 1 , further comprising a storage container. 
     
     
         5 . The system of  claim 1 , wherein the composition remains stable for a period of at least 2 years. 
     
     
         6 . The system of  claim 1 , further comprising one or more pumps. 
     
     
         7 . The system of  claim 6 , wherein the one or more pumps are configured to flow the composition through the system of a rate ranging from about 1 liter per minute to about 50 gallons per minute. 
     
     
         8 . The system of  claim 1 , further comprising a computer processor, memory, circuit, sensor, monitor, real-time feedback loop, pump, actuator, switch, or any combination thereof. 
     
     
         9 . The system of  claim 1 , wherein the system is an automated system. 
     
     
         10 . The system of  claim 9 , wherein the automated system includes artificial intelligence programming configured to continuously regulate, monitor, and modulate the manufacture of the composition in the system. 
     
     
         11 . The system of  claim 1 , further comprising a distilled water production system. 
     
     
         12 . The system of  claim 1 , further comprising a centrifuge. 
     
     
         13 . The system of  claim 12 , wherein the centrifuge is configured to remove insoluble particulate matter. 
     
     
         14 . The system of  claim 12 , wherein the centrifuge is configured to subject the composition to a centrifugal force ranging from about 1000×g to about 100,000×g for a time period ranging from about 1 minute to about 60 minutes. 
     
     
         15 . The system of  claim 1 , wherein the one or more metal nanoparticles comprise gold, silver, magnesium, zinc, calcium, manganese, copper, palladium, nickel, platinum, titanium, cerium, iron, thallium, molybdenum, or an alloy, oxide, hydroxide, sulfide, nitrate, phosphate, fluoride, chloride, or combinations thereof. 
     
     
         16 . The system of  claim 1 , wherein the one or more organic acids comprise tannic acid, citric acid, tri-sodium citric acid, acetic acid, oxalic acid, tartaric acid, succinic acid, maleic acid, fumaric acid, gluconic acid, malic acid, ascorbic acid, benzoic acid, palmitic acid, alginic acid, polyglutamic acid, naphthalenesulfonic acid, methanesulfonic acid, p-toluenesulfonic acid, naphthalenedisulfonic acid, polygalacturonic acid, malonic acid, sulfosalicylic acid, glycolic acid, 2-hydroxy-3-naphthoate, pamoate, salicylic acid, stearic acid, phthalic acid, mandelic acid, or lactic acid, or combinations thereof. 
     
     
         17 . The system of  claim 1 , wherein the one or more metal nanoparticles are present in an amount of less than 1% of the amount of the one or more organic acids. 
     
     
         18 . The system of  claim 1 , wherein the one or more metal nanoparticles are present in the composition in an amount ranging from about 1 ppm to about 20,000 ppm. 
     
     
         19 . The system of  claim 1 , wherein the one or more metal nanoparticles have a diameter ranging from about 1 nm to about 200 nm. 
     
     
         20 . The system of  claim 1 , wherein the one or more metal nanoparticles are silver nanoparticles present in an amount of about 10 ppm to about 20,000 ppm, having a diameter ranging from about 1 nm to about 20 nm, and wherein the one or more organic acids comprise tannic acid present in an amount of about 5 mM to about 30 mM, and citric acid present in an amount of about 3.6% w/v, or tri-sodium citrate present in an amount of about 30 mM to about 300 mM.