Composition and method for compounded therapy

Abstract

A method of producing a compounded medication may include formulating a compounded transdermal cream that includes combining a diclofenac sodium solution and a lidocaine and prilocaine cream. The diclofenac sodium solution may be combined in an amount providing a diclofenac concentration of between approximately 0.1% and approximately 0.75% by weight of the compounded transdermal cream. The lidocaine and prilocaine cream may be combined in an amount providing an approximate equivalent concentration of each of lidocaine and prilocaine between approximately 1.5% and approximately 2.25% by weight of the compounded transdermal cream.

1 - 10 . (canceled) 
     
     
         11 . A compounded transdermal cream comprising:
 diclofenac in an amount between 0.1% and 0.75% by weight of the compounded transdermal cream;   lidocaine and prilocaine in equivalent amounts between 1.5% and 2.25% by weight of the compounded transdermal cream;   DMSO;   propylene glycol;   polyoxyethylene fatty acid esters;   sodium hydroxide;   glycerin, hydroxypropyl cellulose, or a combination thereof;   carboxypolymethylene, carbomer 934, or a combination thereof; and   purified water.   
     
     
         12 . (canceled) 
     
     
         13 . The compounded transdermal cream of  claim 11 , wherein diclofenac is present in an amount between 0.1% and 0.5% by weight of the compounded transdermal cream. 
     
     
         14 . The compounded transdermal cream of  claim 11 , wherein diclofenac is present in an amount between 0.3% and 0.75% by weight of the compounded transdermal cream. 
     
     
         15 . The compounded transdermal cream of  claim 11 , further comprising one or more additional medications comprising one or more nerve depressants, one or more anticonvulsants, or a combination thereof in an amount between 1.0% and 5.0% by weight. 
     
     
         16 . The compounded transdermal cream of  claim 15 , wherein the one or more additional medications is selected from the group consisting of lamotrigine, topiramate, gabapentin, or combination thereof. 
     
     
         17 . The compounded transdermal cream of  claim 16 , wherein diclofenac is present in an amount 0.15% by weight, lidocaine is present in an amount 2.0% by weight, prilocaine is present in an amount 2.0% by weight, and wherein the one or more additional medications is lamotrigine. 
     
     
         18 . The compounded transdermal cream of  claim 16 , wherein diclofenac is present in an amount 0.15% by weight, lidocaine is present in an amount 2.0% by weight, prilocaine is present in an amount 2.0% by weight, and wherein the one or more additional medications is topiramate. 
     
     
         19 . The compounded transdermal cream of  claim 16 , wherein diclofenac is present in an amount 0.15% by weight, lidocaine is present in an amount 2.0% by weight, prilocaine is present in an amount 2.0% by weight, and wherein the one or more additional medications is gabapentin.