Method of synthesizing watermelon seed nanoparticles

Abstract

The watermelon seed nanoparticles may be synthesized by dissolving powdered watermelon seeds in a solvent to produce a first mixture, adding the first mixture dropwise to boiling water under ultrasonic conditions to produce a second mixture, sonicating the second mixture and drying the second mixture to produce watermelon seed nanoparticles. In an embodiment, the watermelon seeds may be Citrullus lanatus seeds. In an embodiment, the watermelon seed nanoparticles may be included in a pharmaceutical composition, such as an antimicrobial or anti-cancer composition.

1 - 16 . (canceled) 
     
     
         17 . A pharmaceutical composition comprising watermelon seed nanoparticles. 
     
     
         18 . The pharmaceutical composition of  claim 17 , wherein the watermelon seed nanoparticles further comprise  Citrullus lanatus  seed nanoparticles. 
     
     
         19 . The pharmaceutical composition of  claim 17 , wherein the watermelon seed nanoparticles have an average diameter of 215 nm. 
     
     
         20 . The pharmaceutical composition of  claim 17 , further comprising a pharmaceutically acceptable carrier. 
     
     
         21 . The pharmaceutical composition of  claim 17 , wherein the watermelon seed nanoparticles are cytotoxic against cancer cells. 
     
     
         22 . The pharmaceutical composition of  claim 21 , wherein the cancer cells are selected from the group consisting of colon cancer cells and breast cancer cells. 
     
     
         23 . The pharmaceutical composition of  claim 17 , wherein the watermelon seed nanoparticles have antimicrobial activity. 
     
     
         24 . The pharmaceutical composition of  claim 23 , wherein the watermelon seed nanoparticles have antimicrobial activity against microbes selected from the group consisting of fungi, gram positive bacteria, and gram negative bacteria.