Slope-Based Compensation

Abstract

A biosensor system determines analyte concentration from an output signal generated from a light-identifiable species or a redox reaction of the analyte. The biosensor system adjusts a correlation for determining analyte concentrations from output signals with one or more index functions extracted from the output signals. The index functions determine at least one slope deviation value, ΔS, or normalized slope deviation from one or more error parameters. The slope-adjusted correlation between analyte concentrations and output signals may be used to determine analyte concentrations having improved accuracy and/or precision from output signals including components attributable to bias.

1 . A method for determining an analyte concentration in a sample, comprising:
 generating at least one output signal value responsive to the concentration of the analyte in the sample;   determining at least one ΔS value from at least one error parameter;   compensating the at least one output signal value with at least one reference correlation and at least one ΔS value; and   determining the analyte concentration in the sample from the at least one output signal value.   
     
     
         2 - 82 . (canceled)