Method and kit for home controlled ovarian stimulation for in vitro fertilization

Abstract

A home controlled ovarian hyperstimulation method for in vitro fertilization (IVF) or egg freezing and a home IVF kit are described herein.

1 - 16 . (canceled) 
     
     
         17 . A kit for home controlled ovarian stimulation in preparation for in vitro fertilization (IVF) or egg freezing, the kit comprising:
 a supply box or pouch comprising:
 a. a medication schedule and directions for self-administration of various medications; 
 b. at least 9 clomiphene citrate oral tablets; 
 c. at least 5 letrozole oral tablets; 
 d. at least 1 GnRH antagonist tablet; 
 e. at least 1 leuprorelin or nafarelin nasal spray device pump; and 
 f. 3 ovulation test kits each ovulation test kit having 2 ovulation tests. 
   
     
     
         18 . The kit of  claim 17 , wherein the supply box or pouch comprises at least 11 compartments each corresponding to one of 11 days of ovulation treatment in preparation for IVF/egg freezing. 
     
     
         19 . The kit of  claim 17 , wherein the GnRH antagonist is elagolix, linzagolix or relugolix. 
     
     
         20 . The kit of  claim 17 , wherein the GnRH antagonist is elagolix. 
     
     
         21 . The kit of  claim 17 , wherein the clomiphene citrate oral tablets are 50 mg tablets, the letrozole oral tablets are 2.5 mg tablets, the GnRH antagonist tablet is a 200 mg tablet, the leuprorelin or nafarelin nasal spray device comprises at least 48 full sprays. 
     
     
         22 . The kit of  claim 17  further comprising a label indicating administration of a 200 mg GnRH antagonist tablet in an amount from 25 mg to 200 mg by vaginal insertion or oral administration in a continuing regimen at a frequency of not more than once per day. 
     
     
         23 . The kit of  claim 22 , wherein the label indicates administration of the GnRH antagonist tablet on day 9 and day 11 of the female patient's menstrual cycle. 
     
     
         24 . The kit of  claim 17  further comprising a label indicating administration of leuprorelin or nafarelin by nasal spray in a continuing regimen at a frequency of at least three sprays per nostril in 12 hour intervals. 
     
     
         25 . The kit of  claim 17 , wherein the supply box or pouch comprises 9 clomiphene citrate tablets and 5 letrozole tablets. 
     
     
         26 . The kit of  claim 17 , wherein the supply box or pouch comprises 18 clomiphene citrate tablets and 10 letrozole tablets. 
     
     
         27 . The kit of  claim 17 , wherein the supply box or pouch comprises 27 clomiphene citrate tablets and 15 letrozole tablets.