Flavored vaporizable formulation

Abstract

There is provided a flavored vaporizable formulation comprising (i) one or more solvents; (ii) a flavor; and (iii) one or more cyclodextrins; wherein the flavored vaporizable formulation contains water in an amount of from 0 to 10 wt. % based on the vaporizable formulation.

1 . A flavored vaporizable formulation comprising:
 (i) one or more solvents;   (ii) a flavor; and   (iii) one or more cyclodextrins;   wherein the flavored vaporizable formulation contains water in an amount of from 0 to 10 wt. % based on the vaporizable formulation;   wherein the flavored vaporizable formulation further comprises nicotine.   
     
     
         2 . A flavored vaporizable formulation according to  claim 1  wherein the total content of cyclodextrins is at least 1 wt. % based on the vaporizable formulation. 
     
     
         3 . A flavored vaporizable formulation according to  claim 1  wherein the one or more cyclodextrins are selected from the group consisting of substituted or unsubstituted (α)-cyclodextrin, substituted or unsubstituted (β)-cyclodextrin, substituted or unsubstituted (γ)-cyclodextrin, and mixtures thereof. 
     
     
         4 . A flavored vaporizable formulation according to  claim 1  wherein the one or more cyclodextrins comprises at least one or more substituted cyclodextrins. 
     
     
         5 . A flavored vaporizable formulation according to  claim 1  wherein the solvent is selected from water, glycerol, propylene glycol and mixtures thereof. 
     
     
         6 . A flavored vaporizable formulation according to  claim 1  wherein the solvent comprises at least glycerol, propylene glycol or a mixture thereof. 
     
     
         7 . A flavored vaporizable formulation according to  claim 1  wherein the solvent is mixture of glycerol and propylene glycol. 
     
     
         8 . A flavored vaporizable formulation according to  claim 1  wherein the flavored vaporizable formulation contains water in an amount of from 0 to 5 wt. % based on the vaporizable formulation. 
     
     
         9 . A flavored vaporizable formulation according to  claim 1  wherein the flavored vaporizable formulation contains water in an amount of from 0 to 1 wt. % based on the vaporizable formulation. 
     
     
         10 . A flavored vaporizable formulation according to  claim 1  wherein the flavored vaporizable formulation contains water in an amount of from 0 to 0.1 wt. % based on the vaporizable formulation. 
     
     
         11 . A flavored vaporizable formulation according to  claim 1  wherein the solvent is present in an amount of at least 75 wt. % based on the flavored vaporizable formulation. 
     
     
         12 . A flavored vaporizable formulation according to  claim 1  wherein the solvent is present in an amount of at least 90 wt. % based on the flavored vaporizable formulation. 
     
     
         13 . A flavored vaporizable formulation according to  claim 1  wherein the one or more flavors are selected from the group consisting of (4-(para-)methoxyphenyl)-2-butanone, vanillin, γ-undecalactone, menthone, 5-propenyl guaethol, menthol, para-mentha-8-thiol-3-one and mixtures thereof. 
     
     
         14 . A flavored vaporizable formulation according to  claim 1  wherein the flavor includes menthol. 
     
     
         15 . A flavored vaporizable formulation according to  claim 1  wherein the one or more flavors are present in a total amount of no greater than 2 wt. % based on the flavored vaporizable formulation. 
     
     
         16 . A flavored vaporizable formulation according to  claim 1  wherein the one or more flavors are present in a total amount of from 0.01 to 1 wt. % based on the flavored vaporizable formulation. 
     
     
         17 . A flavored vaporizable formulation according to  claim 1  wherein the one or more cyclodextrins are selected from the group consisting of substituted (α)-cyclodextrin, substituted (β)-cyclodextrin, substituted (γ)-cyclodextrin, and mixtures thereof. 
     
     
         18 . A flavored vaporizable formulation according to  claim 1  wherein the one or more cyclodextrins is at least 2-hydroxy-propyl-β-cyclodextrin. 
     
     
         19 . A flavored vaporizable formulation according to  claim 1  wherein the one or more cyclodextrins are present in a total amount of at least 7 wt. % based on the flavored vaporizable formulation. 
     
     
         20 . A flavored vaporizable formulation according to  claim 1  wherein the one or more cyclodextrins are present in a total amount of no greater than 10 wt. % based on the flavored vaporizable formulation. 
     
     
         21 . A flavored vaporizable formulation according to  claim 1  wherein the one or more cyclodextrins are present in a total amount of from 2 to 9 wt. % based on the flavored vaporizable formulation. 
     
     
         22 . A process for forming a vapor, the process comprising:
 (a) providing a flavored vaporizable formulation as defined in  claim 1 ; and   (b) vaporizing the flavored vaporizable formulation.   
     
     
         23 . A contained flavored vaporizable formulation comprising
 (a) a container; and   (b) a flavored vaporizable formulation as defined in  claim 1 .   
     
     
         24 . An electronic vapor provision system comprising:
 (a) a vaporizer for vaporizing liquid for inhalation by a user of the electronic vapor provision system;   (b) a power supply comprising a cell or battery for supplying power to the vaporizer; and   (c) a flavored vaporizable formulation comprising:
 (i) one or more solvents; 
 (ii) a flavor; and 
 (iii) one or more cyclodextrins; 
 wherein the flavored vaporizable formulation contains water in an amount of from 0 to 10 wt. % based on the vaporizable formulation. 
   
     
     
         25 . An electronic vapour provision system according to  claim 24  wherein the flavored vaporizable formulation is a flavored vaporizable formulation having a total content of cyclodextrins of at least 1 wt. % based on the vaporizable formulation. 
     
     
         26 . A process for at least one of increasing solubility of a flavor and/or reducing loss of flavor over time during storage from a flavored vaporizable formulation, the process comprising:
 (a) providing a vaporizable material comprising at least one or more solvents;   (b) incorporating into the vaporizable material a flavor and one or more cyclodextrins to form the flavored vaporizable formulation.   
     
     
         27 . A process according to  claim 26  wherein the flavored vaporizable formulation is a flavored vaporizable formulation comprising:
 (i) one or more solvents; 
 (ii) a flavor; and 
 (iii) one or more cyclodextrins; 
 wherein the flavored vaporizable formulation contains water in an amount of from 0 to 10 wt. % based on the vaporizable formulation; 
 wherein the flavored vaporizable formulation further comprises nicotine. 
 
     
     
         28 . Use of one or more cyclodextrins for increasing solubility of a flavor and/or reducing loss of flavor over time during storage from a flavored vaporizable formulation, wherein the flavored vaporizable formulation comprises:
 (i) one or more solvents; and   (ii) a flavor.   
     
     
         29 . Use according to  claim 28  wherein the flavored vaporizable formulation is a flavored vaporizable comprising:
 (i) one or more solvents; 
 (ii) a flavor; and 
 (iii) one or more cyclodextrins; 
 wherein the flavored vaporizable formulation contains water in an amount of from 0 to 10 wt. % based on the vaporizable formulation; 
 wherein the flavored vaporizable formulation further comprises nicotine.