US2020319207A1PendingUtilityA1

Treating schizophrenia based on a panel of biomarkers

Assignee: CAMBRIDGE ENTPR LTDPriority: Dec 20, 2010Filed: Nov 8, 2019Published: Oct 8, 2020
Est. expiryDec 20, 2030(~4.4 yrs left)· nominal 20-yr term from priority
G01N 33/6896G01N 2333/8107G01N 2800/302G01N 33/6893
61
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Claims

Abstract

The invention relates to a method of differential diagnosis of schizophrenia or other psychotic disorder from a further psychiatric disorder.

Claims

exact text as granted — not AI-modified
1 . A method of using one or more analytes selected from: α2 Macroglobulin (A2M), Angiopoietin 2 (ANG2), Betacellulin, Bone morphogenic protein 6 (BMP6), Brain derived neurotrophic factor (BDNF), Carcinoembryonic Antigen (CEA), Epidermal growth factor (EGF), Glutathione S transferase (GST), Haptoglobin (HPT), Interleukin 10 (IL 10), al Antitrypsin (α1AT), CD40 Ligand (CD40L), Cortisol, Connective tissue growth factor (CTGF), Eotaxin 3, Factor VII, Follicle stimulating hormone (FSH), GM-CSF, ICAM 1, IGFBP 2, IL 17, IL 5, Luteinizing Hormone (LH), MIF, NrCAM, Pancreatic Polypeptide (PP), Prostatic acid phosphatise (PAP), RANTES (C-C motif chemokine 5), Resistin, SGOT, Sortilin, Stem Cell Factor (SCF), Thrombopoietin (TPO) and Thrombospondin 1 (TSP1) as a biomarker for the differential diagnosis of schizophrenia or other psychotic disorder from a further psychiatric disorder. 
     
     
         2 . The method of  claim 1 , wherein the one or more analytes are selected from: α2 Macroglobulin (A2M), Angiopoietin 2 (ANG2), Betacellulin, Bone morphogenic protein 6 (BMP6), Brain derived neurotrophic factor (BDNF), Carcinoembryonic Antigen (CEA), Epidermal growth factor (EGF), Glutathione S transferase (GST), Haptoglobin (HPT) and Interleukin 10 (IL 10). 
     
     
         3 - 23 . (canceled)

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