US2020306265A1PendingUtilityA1

Neuroactive steroids, compositions, and uses thereof

Assignee: SAGE THERAPEUTICS INCPriority: Mar 8, 2016Filed: Mar 8, 2017Published: Oct 1, 2020
Est. expiryMar 8, 2036(~9.6 yrs left)· nominal 20-yr term from priority
A61K 31/57A61P 25/14A61K 31/573A61P 25/24A61P 25/22A61P 15/00A61K 31/58A61K 47/40A61K 31/56A61K 9/08A61K 31/568A61K 9/0019
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Claims

Abstract

Described herein are methods of treating a disorder, e.g., tremor, e.g., essential tremor; depression, e.g., postpartum depression; and anxiety disorder, the method comprising administering to a human subject suffering from a disorder, e.g., tremor, e.g., essential tremor, depression, e.g., postpartum depression, an anxiety disorder with a neuroactive steroid or a composition comprising a neuroactive steroid (e.g., pregnanolone, allopregnanolone, alphadalone, ganaxolone, or alphaxolone).

Claims

exact text as granted — not AI-modified
1 - 65 . (canceled) 
     
     
         66 . A method of treating a human subject suffering from depression or an anxiety disorder, comprising administering to the subject a therapeutically effective amount of a compound of the formula

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