Composition and medical product for reducing body weight and body fat, and use of said product

Abstract

Provided is a plant extract composition and a pharmaceutical composition thereof for reducing body weight and body fat, wherein the plant extract composition comprises a green tea extract and a turmeric extract respectively 30 wt % to 75 wt % and 20 wt % to 55 wt % of a total weight of the composition. In diet-induced obesity models, either obesity is induced first or simultaneously with administration, the plant extract composition and a pharmaceutical composition thereof can reduce body weight and body fat more significantly than a single plant extract or commercially available weight loss drugs.

1 - 33 . (canceled) 
     
     
         34 . A composition for reducing body weight or body fat, comprising epigallocatechin gallate (EGCG), curcumin, and a pharmaceutically acceptable excipient. 
     
     
         35 . The composition of  claim 34 , wherein the value of the weight ratio between curcumin and EGCG in the composition is 0.32 to 3.2. 
     
     
         36 . The composition of  claim 34 , wherein the value of the weight ratio between curcumin and EGCG in the composition is 0.4. 
     
     
         37 . The composition of  claim 34 , wherein the value of the weight ratio between curcumin and EGCG in the composition is 3.2. 
     
     
         38 . The composition of  claim 34 , wherein the pharmaceutically acceptable excipient comprises polyoxyethylene stearates, piperine, or a combination thereof. 
     
     
         39 . The composition of  claim 38 , wherein the polyoxyethylene stearate is polyoxyethylene (32) stearate, polyoxyethylene (40) stearate, or a combination thereof. 
     
     
         40 . The composition of  claim 34 , wherein the composition further comprises resveratrol. 
     
     
         41 . The composition of  claim 34 , wherein the composition is formulated for oral administration or for injection. 
     
     
         42 . A method for reducing body weight or body fat in a subject, the method comprising administering to a subject in need thereof an effective amount of the composition of  claim 34 . 
     
     
         43 . The method of  claim 42 , wherein the value of the weight ratio between curcumin and EGCG in the composition is 0.32 to 3.2. 
     
     
         44 . The method of  claim 42 , wherein the value of the weight ratio between curcumin and EGCG in the composition is 0.4. 
     
     
         45 . The method of  claim 42 , wherein the value of the weight ratio between curcumin and EGCG in the composition is 3.2. 
     
     
         46 . The method of  claim 42 , wherein the pharmaceutically acceptable excipient comprises polyoxyethylene stearates, piperine, or a combination thereof. 
     
     
         47 . The method of  claim 46 , wherein the polyoxyethylene stearate is polyoxyethylene (32) stearate, polyoxyethylene (40) stearate, or a combination thereof. 
     
     
         48 . The method of  claim 42 , wherein the composition further comprises resveratrol. 
     
     
         49 . The method of  claim 42 , wherein the composition is administered to the subject orally or by injection. 
     
     
         50 . The method of  claim 42 , wherein the subject is a human subject.