Manufacturing methods, compositions, and medical applications of orally administered cannabis pharmaceuticals using representative/total/complete cannabis extractions (cannabis infused pills)

Abstract

Disclosed herein are embodiments of cannabis extraction methods, apparatuses for extracting cannabis, and methods of using cannabis extracts.

1 .- 42 . (canceled) 
     
     
         43 . A method of preparing a decarboxylated  cannabis  material, comprising:
 adding a  cannabis  material to a reaction chamber;   treating the reaction chamber with an inert gas;   initiating a decarboxylation process on the  cannabis  material in the presence of the inert gas to produce a decarboxylated  cannabis  material and decarboxylation byproducts within the reaction chamber;   condensing the decarboxylated  cannabis  material within the reaction chamber;   removing the decarboxylation byproducts from the reaction chamber; and   removing the decarboxylated  cannabis  material from the reaction chamber.   
     
     
         44 . The method of  claim 43 , wherein the  cannabis  material is a  cannabis  flower or a  cannabis  extract. 
     
     
         45 . The method of  claim 44 , wherein the  cannabis  flower is selected from the group consisting of  Cannabis sativa, Cannabis indica, Cannabis ruderalis,  hybrids thereof, and combinations thereof. 
     
     
         46 . The method of  claim 43 , wherein the method further comprises applying an extraction process to a  cannabis  flower to yield the  cannabis  material. 
     
     
         47 . The method of  claim 46 , wherein the extraction process is a solvent-based extraction. 
     
     
         48 . The method of  claim 47 , wherein the solvent-based extraction comprises a solvent selected from the group consisting of an alcohol solvent, a lipid solvent, a hydrocarbon solvent, a CO 2  solvent, a water-based solvent, and combinations thereof. 
     
     
         49 . The method of  claim 46 , wherein the extraction process is a solventless extraction process. 
     
     
         50 . The method of  claim 49 , wherein the solventless extraction process is selected from the group consisting of a heat extraction, an unheated extraction, a rosin tech extraction, and combinations thereof. 
     
     
         51 . The method of  claim 43 , wherein the  cannabis  material is not dried. 
     
     
         52 . The method of  claim 43 , wherein the  cannabis  material is dried. 
     
     
         53 . The method of  claim 43 , wherein the reaction chamber during the decarboxylation process is airtight. 
     
     
         54 . The method of  claim 53 , wherein the reaction chamber during the decarboxylation process is pressurized. 
     
     
         55 . The method of  claim 53 , wherein the reaction chamber is purged following the decarboxylation process. 
     
     
         56 . The method of  claim 43 , wherein the decarboxylation byproducts comprise CO 2 . 
     
     
         57 . The method of  claim 56 , wherein the CO 2  is removed through a filter comprising pores that allow for removal of the CO 2  from the reaction chamber and prevents removal or escape of the decarboxylated  cannabis  material from the reaction chamber. 
     
     
         58 . The method of  claim 57 , wherein the pores are from about 29 Å 2  to about 31 Å 2 . 
     
     
         59 . The method of  claim 43 , wherein the decarboxylation process comprises using a targeted enzyme or cofactor. 
     
     
         60 . The method of  claim 43 , wherein the decarboxylation process further comprises application of H 2 O as a catalyst. 
     
     
         61 . The method of  claim 43 , wherein the decarboxylation process further comprises stirring the  cannabis  material. 
     
     
         62 . The method of  claim 43 , wherein the decarboxylated  cannabis  material comprises at least one cannabinoid and at least one terpene. 
     
     
         63 . The method of  claim 43 , wherein the decarboxylated  cannabis  material comprises cannabinoids, terpenes/terpenoids, amino acids, nitrogenous compounds, simple alcohols, aldehydes, ketones, esters, lactones, and acids, fatty acids, steroids, non-cannabinoid phenols, pigments, flavonoids, vitamins, proteins, enzymes, glycoproteins, and hydrocarbons. 
     
     
         64 . The method of  claim 43 , wherein the decarboxylated  cannabis  material partially comprises non-decarboxylated  cannabis  material. 
     
     
         65 . A method of preparing a decarboxylated  cannabis  material, comprising:
 adding a  cannabis  material to a reaction chamber;   initiating a decarboxylation process on the  cannabis  material in the presence of vacuum to produce a decarboxylated  cannabis  material and decarboxylation byproducts within the reaction chamber;   condensing the decarboxylated  cannabis  material within the reaction chamber;   removing the decarboxylation byproducts from the reaction chamber; and   removing the decarboxylated  cannabis  material from the reaction chamber.