Personalized prosthesis and methods of use

Abstract

A personalized prosthesis for implantation at a treatment site of a patient includes a self-expanding mesh or membrane having collapsed and expanded configurations. The collapsed configuration is adapted to be delivered to the treatment site, and the expanded configuration engages the personalized prosthesis with the treatment site. The mesh or membrane is personalized to match the treatment site in the expanded configuration, and has an outer surface that substantially matches the treatment site shape and size. The self-expanding mesh or membrane forms a central lumen configured to allow blood or other body fluids to flow therethrough. Methods of manufacturing and delivery of the personalized prosthesis are also disclosed.

1 . A personalized implant, the implant comprising:
 a radially expandable prosthesis having a lumen extending therethrough, an expanded configuration and a collapsed configuration, wherein the prosthesis is personalized such that the prosthesis matches a shape and a volume of a treatment site in the expanded configuration.   
     
     
         2 . A method for treating an aneurysm having walls with contours, the method comprising
 providing a personalized prosthesis having walls with contours;   delivering the personalized prosthesis to the aneurysm; and   radially expanding the personalized prosthesis into engagement with the aneurysm such that the contours of the walls of the personalized prosthesis substantially match the contours of the walls of the aneurysm.   
     
     
         3 . A method for fabricating a personalized implant, the method comprising:
 obtaining an image of a treatment site, the treatment site having contours; and   forming the personalized implant to have contours that substantially match the contours of the treatment site based on the obtained image.