Ointment containing an oxazole compound

Abstract

An ointment is provided. The ointment stably comprises an oxazole compound that has specific inhibitory activity against PDE4 and that is represented by the following formula (11). The ointment can be efficiently absorbed into the skin.

1 . An ointment comprising an oxazole compound represented by the following formula (11): 
       
         
           
           
               
               
           
         
       
     
     
         2 . The ointment according to  claim 1 , comprising the oxazole compound dissolved in a base component. 
     
     
         3 . The ointment according to  claim 2 , wherein the base component comprises a solvent for dissolving the oxazole compound in the solvent, and an ointment base for dispersing or dissolving the solvent in the ointment base. 
     
     
         4 . The ointment according to  claim 3 , wherein the ointment base comprises a hydrocarbon. 
     
     
         5 . The ointment according to  claim 3 , wherein the solvent comprises a polar compound that is a liquid at room temperature. 
     
     
         6 . The ointment according to  claim 3 , wherein the ointment base is an ointment base for dispersing the solvent in the ointment base, and the solvent in the form of droplets, in which the oxazole compound is dissolved, is dispersed in the ointment base. 
     
     
         7 . The ointment according to  claim 3 , wherein the ointment base comprises at least beeswax. 
     
     
         8 . The ointment according to  claim 7 , wherein the beeswax is not chemically bleached. 
     
     
         9 . The ointment according to  claim 1 , for use in the treatment and/or prevention of eczema and dermatitis.