Method and device for introducing at least one quantitatively determined exogenous substance into an endogenous liquid

Abstract

The present invention relates to a device for recognising, measuring and quantitatively determining at least one exogenous substance in an endogenous liquid. According to the invention, the device comprises: —a means for suctioning (1) an endogenous liquid containing at least one exogenous substance; —a means for collecting (2) the endogenous liquid containing at least one exogenous substance; —a spectrometer (3), preferably a Raman or infrared spectrometer, capable of acquiring and analysing said collected liquid; —a database-type data storage means comprising spectra relating to at least one exogenous substance; —a means for comparison between the spectrum or spectra acquired and the spectrum or spectra of the database; —a means (4) for controlled introduction of at least one exogenous substance into the endogenous liquid, as a function of the result of said comparison. The invention also relates to the method implemented by such a device.

1 .- 10 . (canceled) 
     
     
         11 . A device for recognizing, measuring and dosing at least one exogenous substance into an endogenous liquid, comprising:
 a means for suction of an endogenous liquid containing at least one exogenous substance;   a collector for the endogenous liquid;   a spectrometer configured to acquire and analyze the collected endogenous liquid;   a processor containing a database comprising spectra relating to at least one exogenous substance and configured to compare spectrum or spectra acquired by the spectrometer and the spectrum or spectra in the database;   at least one pump for controlled introduction of at least one exogenous substance into the endogenous liquid, as a function of the result of the spectral comparison.   
     
     
         12 . The device according to claim  1 , wherein the spectrometer is a Raman or infrared spectrometer. 
     
     
         13 . The device according to claim  1  further comprising a display of a measurement of, a dose of, a nature of at least one exogenous substance contained in the endogenous liquid. 
     
     
         14 . The device according to claim  1  wherein the pump if configured to provide a variable and controlled rate of introduction of the exogenous substance. 
     
     
         15 . The device according to claim  1  wherein the pump is controlled by the spectrometer. 
     
     
         16 . The device according to claim  1  further comprising a device configured to vary the temperature of the exogenous substance. 
     
     
         17 . The device according to claim  1  wherein the pump enables monitoring over time and/or in terms of amount of the exogenous substance. 
     
     
         18 . The device according to claim  1  wherein the stored spectra are correlated to variations in temperature and/or to variations in acidity of the endogenous liquid. 
     
     
         19 . The device according to claim  1  further comprising a centrifuge for centrifuging the endogenous liquid. 
     
     
         20 . The device according to claim  1  further comprising additional pumps for controlled introduction of an exogenous substance, at least one of which is mounted on a carrier structure and each being connected to the processor. 
     
     
         21 . The device according to claim  1  wherein the exogenous liquid comprises at least one antibiotic. 
     
     
         22 . A process for modifying the composition of an endogenous liquid by an exogenous substance comprising:
 sucking an endogenous liquid from a mammal into a device;   collecting the liquid;   analyzing the liquid using spectrometry to obtain a spectra relating to at least one measured exogenous substance;   comparing the obtained spectra to at least one stored spectrum with at least one reference spectrum of an element of the endogenous liquid;   introducing at least one exogenous substance in a rate-controlled manner into the endogenous liquid emerging from the device, as a function of the result of the spectral comparison.