Abdominal wall treatment devices

Abstract

Devices and methods for treating or repairing openings in an body wall are provided. The devices and methods can include acellular tissue matrices. The tissue matrices can be positioned within the abdominal opening and can be used to close the opening.

1 . An abdominal or fascia treatment device, comprising:
 a sheet of acellular tissue matrix, wherein the sheet of acellular tissue matrix includes an elongated opening and, on opposite sides of the opening, multiple reinforced holes for receiving sutures.   
     
     
         2 . The device of  claim 1 , wherein the holes include two or more rows of holes positioned on each side of the elongated opening. 
     
     
         3 . The device of  claim 1 , wherein the sheet comprises two or more pieces of acellular tissue matrix. 
     
     
         4 . The device of  claim 1 , wherein the acellular tissue matrix is a dermal acellular tissue matrix. 
     
     
         5 . The device of  claim 4 , wherein the dermal tissue matrix is a human tissue matrix. 
     
     
         6 . The device of  claim 4 , wherein the dermal tissue matrix is a porcine tissue matrix. 
     
     
         7 . The device of  claim 1 , wherein the reinforced holes include an adhesive. 
     
     
         8 . The device of  claim 7 , wherein the adhesive comprises a cyanoacrylate adhesive. 
     
     
         9 . The device of  claim 7 , wherein the adhesive comprises fibrin. 
     
     
         10 . The device of  claim 1 , wherein rims or edges of the holes are crosslinked. 
     
     
         11 . The device of  claim 1 , wherein the elongated opening extends across a portion of a center of the sheet of acellular tissue matrix and is configured to provide access to a body cavity in an open configuration and close the body cavity in a closed configuration. 
     
     
         12 . A method of treating an abdominal or fascia defect, comprising:
 positioning a sheet of acellular tissue matrix in or on a defect in a body cavity, wherein the sheet of acellular tissue matrix includes an elongated opening and, on opposite sides of the opening, multiple rows of reinforced holes for receiving sutures; and   securing the acellular tissue matrix to tissue surrounding a peripheral border of the defect to close the defect.   
     
     
         13 . The method of  claim 12 , wherein the reinforced holes include an adhesive. 
     
     
         14 . The method of  claim 13 , wherein the adhesive comprises a cyanoacrylate adhesive. 
     
     
         15 . The method of  claim 14 , wherein the adhesive comprises fibrin. 
     
     
         16 . The method of  claim 12 , wherein the acellular tissue matrix is secured by attaching at least one first suture to a first row of reinforced holes. 
     
     
         17 . The method of  claim 16 , further comprising attaching at least one second suture to a second row of reinforced holes. 
     
     
         18 . The method of  claim 17 , wherein the at least one first suture is removed after attaching the at least one second suture. 
     
     
         19 . The method of  claim 12 , wherein the sheet comprises two or more pieces of acellular tissue matrix. 
     
     
         20 . The method of  claim 12 , wherein rims or edges of the holes are crosslinked. 
     
     
         21 . The method of  claim 12 , further comprising:
 closing the elongated opening with at least one suture attached to at least one row of reinforced holes.   
     
     
         22 . The method of  claim 21 , further comprising:
 removing the at least one suture to open the elongated opening; and   accessing the abdominal cavity through the elongated opening.