US2019381124A1PendingUtilityA1

Compositions and methods for the treatment of orthopedic ailments

Assignee: K L R M LLCPriority: Sep 29, 2016Filed: Aug 14, 2019Published: Dec 19, 2019
Est. expirySep 29, 2036(~10.2 yrs left)· nominal 20-yr term from priority
A61K 36/9068A61K 36/906A61K 31/198A61K 36/77A61P 19/10A61K 36/185
62
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Claims

Abstract

A composition for enhancing treatment of orthopedic ailments stimulates iNOS and enhances treatment of orthopedic ailments when a pharmaceutically effective amount is administered over a sufficient period of time. The composition comprises ginger, Muira puama, Paullinia cupana, and at least one of the group consisting of L-arginine and L-citrulline.

Claims

exact text as granted — not AI-modified
1 . A composition for enhancing treatment of orthopedic ailments, wherein administration of a pharmaceutically effective amount of the composition over a sufficient period of time stimulates iNOS and enhances treatment of orthopedic ailments, comprising:
 ginger or a ginger derivative;     Muira puama;        Paullinia cupana ; and   at least one of the group consisting of L-arginine and L-citrulline.   
     
     
         2 . (canceled) 
     
     
         3 . The composition according to  claim 1 , wherein the composition comprises 250 mg to 2 g the ginger or ginger derivative. 
     
     
         4 . The composition according to  claim 1 , including 10 mg to 3 g of L-arginine, L-citrulline, or a mixture of L-arginine and L-citrulline. 
     
     
         5 . The composition according to  claim 1 , including 10 mg to 2 g of L-arginine, L-citrulline, or a mixture of L-arginine and L-citrulline 
     
     
         6 . The composition according to  claim 1 , including 100 mg to 3 g of  Muira puama.    
     
     
         7 . The composition according to  claim 1 , including 500 mg to 1.5 g of  Muira puama.    
     
     
         8 . The composition according to  claim 1 , including at least 250 mg of  Paullinia cupana.    
     
     
         9 . The composition according to  claim 1 , including 500 mg of  Paullinia cupana.    
     
     
         10 . The composition according to  claim 1 , including 250 mg to 2 g of ginger or ginger derivative, 250 mg to 2 g of L-arginine, L-citrulline, or mixture of L-arginine and L-citrulline, 500 mg to 1.5 g of  Muira puama , and 500 mg of  Paullinia cupana.    
     
     
         11 . The composition according to  claim 1 , wherein administration of the pharmaceutically effective amount of the composition over the sufficient period of time increases the rate of bone fracture healing. 
     
     
         12 . The composition according to  claim 1 , wherein administration of the pharmaceutically effective amount of the composition over the sufficient period of time is effective in treatment of osteoporosis. 
     
     
         13 - 24 . (canceled)

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