Topical preparation for pain relief

Abstract

A composition for pain relief including synergistically effective amounts of an amino benzoate local anesthetic, methylsulfonylmethane (MSM), and ethoxydiglycol. A method of treating pain, by applying the composition to skin in an area of pain, and blocking nerve signals. A method of improving range of motion in an individual, by applying the composition to skin, relieving pain, and allowing the individual to have an improved range of motion at an area of pain.

1 ) A composition for pain relief comprising an amino benzoate local anesthetic component, and a penetrating enhancer component comprising methylsulfonylmethane (MSM), ethoxydiglycol, and propylene glycol,
 wherein the composition is formulated for topical delivery; and   wherein the components of the composition are effective to work together to deeply penetrate the skin of a subject, and to provide pain relief.   
     
     
         2 ) The composition of  claim 1 , wherein said amino benzoate local anesthetic component is administered in the amount of 0.5-4.5 mg/kg/dose, and said MSM is administered in the amount of up to 6 g/day. 
     
     
         3 ) The composition of  claim 1 , wherein said amino benzoate local anesthetic is selected from the group consisting of lidocaine, benzocaine 5-10%, prilocaine 1%, tetracaine 2%, and combinations thereof. 
     
     
         4 ) The composition of  claim 1 , wherein said composition further includes at least one excipient selected from the group consisting of water, polyacrylamide, C13-14 isoparaffin, laureth 7, triethanolamine, emu oil, tea tree oil,  Arnica montana  extract, ethylhexylglycerin, phenoxyethanol, isopropyl palmitate, stearic acid, glucosamine sulfate, chondroitin sulfate, and combinations thereof. 
     
     
         5 ) The composition of  claim 1 , wherein said composition includes one or more of 1-50% deionized water, 1-20% polyacrylamide, 1-20% CI 3-14 isoparaffin, 1-20% laureth-7, 1-20% lidocaine HCl, 1-10% MSM, 0.10-5% ethoxydiglycol, 0.10-5% triethanolamine, 0.10-5% emu oil, 0.10-5% tea tree oil, 0.10-5%  Arnica Montana  extract, 0.10-5% ethylhexylglycerin, 0.10-5% phenoxyethanol, 0.10-5% isopropyl palmitate, 0.05-5% stearic acid, 0.05-5% glucosamine sulfate, and 0.05-5% chondroitin sulfate. 
     
     
         6 ) The composition of  claim 1 , wherein said composition is in an administration form chosen from the group consisting of a cream, a gel, a patch, or a spray. 
     
     
         7 ) The composition of  claim 1 , wherein said composition has a release profile selected from the group consisting of rapid release, extended release, and sustained release. 
     
     
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