Apoaequorin and vitamin d-containing compositions and methods of using same

Abstract

Compositions containing apoaequorin and vitamin D and methods for their use in treating symptoms and disorders related to calcium imbalances and vitamin D deficiency associated with, for example, sleep quality, energy quality, mood quality, memory quality or pain are provided by the present invention

1 . A composition for treating a symptom or disorder associated with at least one of calcium imbalance and vitamin D deficiency, comprising: (a) an effective amount of apoaequorin; (b) an effective amount of vitamin D; and (c) an acceptable carrier. 
     
     
         2 . The composition according to  claim 1 , wherein the composition is in the form of a unit dosage containing said effective amounts of the apoaequorin and vitamin D. 
     
     
         3 . The composition according to  claim 2 , wherein: (a) the effective amount of apoaequorin in the unit dosage is about 10 mg to about 50 mg; and (b) the effective amount of vitamin D in the unit dosage is about 25 mcg to about 75 mcg. 
     
     
         4 . The composition according to  claim 3 , wherein: (a) the effective amount of apoaequorin in the unit dosage is about 20 mg; and (b) the effective amount of vitamin D in the unit dosage is about 50 mcg. 
     
     
         5 . The composition according to  claim 1 , wherein the vitamin D is in the form of D3 cholecalciferol. 
     
     
         6 . The composition according to  claim 1 , wherein the unit dosage is a capsule. 
     
     
         7 . The composition according to  claim 1 , wherein the composition is a nutraceutical composition. 
     
     
         8 . A method for treating a symptom or disorder associated with at least one of calcium imbalance and vitamin D deficiency, comprising administering to a subject in need of such treatment an effective amount of a composition according to  claim 1 . 
     
     
         9 . The method according to  claim 8 , wherein the symptom or disorder is sleep-related and administration of the composition to said subject improves sleep quality in the subject. 
     
     
         10 . The method according to  claim 8 , wherein the symptom or disorder is energy-related and administration of the composition to said subject improves energy quality in the subject. 
     
     
         11 . The method according to  claim 8 , wherein the symptom or disorder is mood-related and administration of the composition to said subject improves mood quality in the subject. 
     
     
         12 . The method according to  claim 8 , wherein the symptom or disorder is pain-related and administration of the composition to said subject alleviates pain in the subject. 
     
     
         13 . The method according to  claim 8 , wherein the symptom or disorder is memory-related and administration of the composition to said subject improves memory quality in the subject. 
     
     
         14 . The method according to  claim 8 , wherein the symptom or disorder is related to neuronal excitability, muscle contraction, membrane permeability, cell division, hormone secretion, bone mineralization, or cell death following ischemia. 
     
     
         15 .- 18 . (canceled) 
     
     
         19 . The method according to  claim 8 , wherein the composition is in the form of a unit dosage containing said effective amounts of the apoaequorin and vitamin D. 
     
     
         20 . The method according to  claim 19 , wherein: (a) the effective amount of apoaequorin in the unit dosage is about 10 mg to about 50 mg; and (b) the effective amount of vitamin D in the unit dosage is about 25 mcg to about 75 mcg. 
     
     
         21 . The method according to  claim 19 , wherein: (a) the effective amount of apoaequorin in the unit dosage is about 20 mg; and (b) the effective amount of vitamin D in the unit dosage is about 50 mcg. 
     
     
         22 . The method according to  claim 8 , wherein the vitamin D is in the form of D3 cholecalciferol. 
     
     
         23 . The method according to  claim 19 , wherein the unit dosage is a capsule. 
     
     
         24 . The method according to  claim 8 , wherein the composition is a nutraceutical composition.