Devices and methods for minimally invasive tissue removal

Abstract

A medical device for minimally invasive removal of tissue from a body lumen, can include: a sheath having a proximal and a distal end; and a tool configured to pass through the sheath and configured to transition from a crimped state to a deployed state and to a closed state, wherein the tool forms an aperture at a distal end, the distal end of the tool having at least one tube loop and at least one wire loop, wherein the tool is configured to dissect tissue in the deployed state.

1 . A medical device for minimally invasive removal of tissue from a body lumen, comprising:
 a sheath having a proximal and a distal end; and   a tool configured to pass through the sheath and configured to transition from a crimped state to a deployed state and to a closed state, wherein the tool forms an aperture at a distal end, the distal end of the tool having at least one tube loop and at least one wire loop,   wherein the tool is configured to dissect tissue in the deployed state.   
     
     
         2 - 30 . (canceled) 
     
     
         31 . The device of  claim 1 , wherein the tool in the deployed state has a radial force and wherein the tool is configured to allow adjustment of at least one of the radial force and the aperture. 
     
     
         32 . The device of  claim 31 , wherein the at least one tube loop has an adjustable outward angle and wherein the adjustment of the radial force takes place by pushing the at least one wire loop along a longitudinal axis of the sheath. 
     
     
         33 . The device of  claim 31 , wherein the at least one wire loop has varying degrees of rigidity and wherein the adjustment of the radial force is by shifting a location of segments of the at least one wire loop. 
     
     
         34 . The device of  claim 1 , the at least one tube loop and the at least one wire loop comprises three levels of loops. 
     
     
         35 . The device of  claim 34 , wherein the tool comprises a first level of at least one tube loop and a second level of at least one tube loop that proceeds from a distal end of the first level of the at least one tube loop in the deployed state, and
 wherein the at least one wire loop extends from the distal end of the second level of at least one tube loop in the deployed state.   
     
     
         36 . The device of  claim 1 , wherein the tool includes a directional feature that ensures order and orientation of the at least one tube loop. 
     
     
         37 . The device of  claim 36 , further comprising a multilumen segment that is configured to house at least a portion of the at least one tube loop,
 wherein the directional feature includes the tube loop having a portion with an oval cross-sectional shape and a central lumen of the multilumen segment having an oval cross-sectional shape.   
     
     
         38 . The device of  claim 1 , further comprising a multilumen segment that is configured to house at least a portion of the tube loop. 
     
     
         39 . The device of  claim 38 , further comprising connections between each of adjacent tube loops, the connections being distal to the multilumen segment. 
     
     
         40 . The device of  claim 1 , wherein the at least one tube loop forms a cross-section of the device that has a generally circular shape. 
     
     
         41 . The device of  claim 1 , wherein the at least one tube loop is expandable. 
     
     
         42 . The device of  claim 41 , wherein the at least one tube loop is radially expandable. 
     
     
         43 . The device of  claim 1 , wherein the tool is at least one of self-expandably, slideably and rotatably disposed in the sheath. 
     
     
         44 . The device of  claim 1 , wherein the at least one tube loop is configured to remove a plaque from an arterial wall. 
     
     
         45 . The device of  claim 1 , wherein the at least one tube loop is adjustable. 
     
     
         46 . The device of  claim 1 , wherein the at least one tube loop comprises a sharp element at the distal end. 
     
     
         47 . The device of  claim 46 , wherein the distal end of the at least one tube loop includes a blunt portion that is oriented away from an arterial wall of the body lumen and a sharp portion having the sharp element that protrudes into the tissue to be removed. 
     
     
         48 . The device of  claim 1 , wherein the at least one tube loop is an arch having two legs along a longitudinal axis of the sheath in the deployed state. 
     
     
         49 . The device of  claim 48 , wherein the arch has a curved symmetrical structure spanning an opening. 
     
     
         50 . The device of  claim 1 , wherein the at least one wire loop is a monofilament wire of shape memory material. 
     
     
         51 . The device of  claim 50 , wherein the at least one wire loop is made of nitinol. 
     
     
         52 . The device of  claim 1 , wherein the at least one tube loop is hollow to surround the at least one wire loop in the crimped state, and wherein the at least one wire loop is exit-able/extendible from the at least one tube loop. 
     
     
         53 . The device of  claim 1 , wherein a diameter of the at least one wire loop is less than an inner diameter of the at least one tube loop. 
     
     
         54 . The device of  claim 1 , wherein the minimally invasive removal of tissue is percutaneous access removal of tissue. 
     
     
         55 . The device of  claim 1 , wherein the device is configured for the minimally invasive removal of tissue in an endarterectomy. 
     
     
         56 . The device of  claim 1 , wherein the device is configured for the minimally invasive removal of blood clot in an embolectomy. 
     
     
         57 . The device of  claim 1 , wherein the device is configured for the minimally invasive removal of renal calculi in an urolithotomy. 
     
     
         58 . The device of  claim 1 , wherein the device is configured for the minimally invasive removal of tissue in a pulmonary embolism.