Method For The Management Of Cancer And Cancer Treatment-Related Comorbidities

Abstract

A method for the management of cancer and treatment of cancer comorbidities, including but not limited to cancer-related fatigue, cachexia, anorexia, pain, anemia, asthenia, depression, muscle weakness, nausea, vomiting, skin, and skin appendages adverse reactions; the method including the administration by the conventional and non-conventional oral, topical, parenteral routes and intra-tumoral injection, or in combination thereof, or the administration as adjuvant potentiator in other therapies using the forenamed routes, of a composition containing as active ingredient an extract of Allium species, which contains querceting, an extract of Citrus species and an extract of Pauffinia species and an extract of Theobroma species.

What is claimed is: 
     
         1 . A method for managing cancer and for treating at least one cancer comorbidity selected from the group consisting of cachexia, anorexia, pain, anemia, asthenia, depression, muscle weakness, nausea, vomiting, adverse skin reactions, adverse skin appendages reactions, and a combination thereof in a subject in need thereof, the method comprising:
 administering to the subject, by an oral route, a topical route, a parenteral route, an intra-tumoral injection, or a combination thereof, a composition comprising as active ingredients an extract of  Allium  species comprising quercetin, an extract of  Citrus  species, an extract of  Pauffinia  species, and an extract of  Theobroma  species.   
     
     
         2 . The method according to  claim 1 , wherein the composition contains the extract of the  Allium  species comprising quercetin, the extract of the  Citrus  species, an atomized extract of the  Pauffinia  species and an atomized extract of the  Theobroma  species. 
     
     
         3 . The method according to  claim 1 , wherein the composition comprises:
 from 30% to 93% by weight of the extract of the  Allium  species comprising quercetin,   from 3% to 33% by weight of the extract of the  Citrus  species,   from 0.10% to 2.5% by weight of the atomized extract of the  Paullinia  species, and   from 0.10% to 2.5% by weight of the atomized extract of the  Theobroma  species,   wherein the percentages are based on the total weight of the four active ingredients.   
     
     
         4 . The method according to  claim 1 , wherein the at least one cancer comorbidity comprises pain, depression, muscle weakness, adverse skin reactions, adverse skin appendages reactions, or a combination thereof. 
     
     
         5 . The method according to  claim 1 , wherein the extract of  Allium  species is an extract of  Allium  cepa. 
     
     
         6 . The method according to  claim 1 , wherein the extract of  Citrus  species is an extract of  Citrus lemon.    
     
     
         7 . The method according to  claim 1 , wherein the extract of  Pauffinia  species is an extract of  Pauffinia cupana.    
     
     
         8 . The method according to  claim 1 , wherein the extract of  Theobroma  species is an extract of  Theobroma cacao.    
     
     
         9 . The method according to  claim 1 , wherein the composition comprises:
 approximately 87% by weight of an extract of  Allium cepa  comprising quercetin;   approximately 12% by weight of an extract of  Citrus lemon;      approximately 0.5% by weight of an extract of  Pauffinia cupana ; and   approximately 0.5% by weight of an extract of  Theobroma cacao,      wherein the percentages are based on the total weight of the four active ingredients.   
     
     
         10 . A method for managing cancer and for treating at least one cancer comorbidity in a subject in need thereof, the method comprising:
 administering to the subject a composition comprising an extract of  Allium  species, an extract of  Citrus  species, an extract of  Pauffinia  species, and an extract of  Theobroma  species.   
     
     
         11 . The method according to  claim 10 , wherein the extract of  Allium  species comprises quercetin. 
     
     
         12 . The method according to  claim 10 , wherein the administering is performed orally, topically, or parenterally. 
     
     
         13 . The method according to  claim 10 , wherein at least one of the extract of  Pauffinia  species or the extract of  Theobroma  species is atomized. 
     
     
         14 . The method according to  claim 10 , wherein the composition comprises:
 from 30% to 93% by weight of the extract of the  Allium  species;   from 3% to 33% by weight of the extract of the  Citrus  species;   from 0.10% to 2.5% by weight of the extract of the  Pauffinia  species; and   from 0.10% to 2.5% by weight of the extract of the  Theobroma  species,   wherein the percentages are based on the total weight of the extract of  Allium cepa , the extract of  Citrus lemon , the extract of  Pauffinia cupana , and the extract of  Theobroma cacao.      
     
     
         15 . The method according to  claim 10 , wherein the composition consists of the extract of  Allium  species, the extract of  Citrus  species, the extract of  Pauffinia  species, and the extract of  Theobroma  species. 
     
     
         16 . The method according to  claim 10 , wherein the at least one cancer comorbidity is cancer-related fatigue, cachexia, anorexia, pain, anemia, asthenia, depression, muscle weakness, nausea, vomiting, adverse skin reactions, adverse skin appendages reactions, or a combination thereof. 
     
     
         17 . A method for managing cancer and for treating at least one cancer comorbidity in a subject in need thereof, the method comprising:
 administering to the subject a composition comprising:
 from 30% to 93% by weight of an extract of  Allium cepa  comprising quercetin; 
 from 3% to 33% by weight of an extract of  Citrus lemon;    
 from 0.10% to 2.5% by weight of an extract of  Pauffinia cupana ; and 
 from 0.10% to 2.5% by weight of an extract of  Theobroma cacao,    
   wherein the percentages are based on the total weight of the extract of  Allium cepa , the extract of  Citrus lemon , the extract of  Pauffinia cupana , and the extract of  Theobroma cacao.      
     
     
         18 . The method according to  claim 17 , wherein the composition comprises:
 approximately 87% by weight of the extract of  Allium cepa  comprising quercetin;   approximately 12% by weight of the extract of  Citrus lemon;      approximately 0.5% by weight of the extract of  Pauffinia cupana ; and   approximately 0.5% by weight of the extract of  Theobroma cacao.      
     
     
         19 . The method according to  claim 17 , wherein the composition consists of the extract of  Allium cepa  comprising quercetin, the extract of  Citrus lemon , the extract of  Pauffinia cupana ; and the extract of  Theobroma cacao.    
     
     
         20 . The method according to  claim 17 , wherein the administering comprises administering the composition to the subject daily for at least 6 months.