US2019314280A1PendingUtilityA1

Aerosol liposome of marine extract and method of producing the same

Assignee: FISHERIES RES INSTITUTE COUNCIL OF AGRICULTUREPriority: Apr 20, 2016Filed: May 28, 2019Published: Oct 17, 2019
Est. expiryApr 20, 2036(~9.7 yrs left)· nominal 20-yr term from priority
A61K 45/06A61K 9/0073A61K 35/60A61K 9/127A61K 31/685A61K 9/12A61K 35/618
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Claims

Abstract

An aerosol liposome of a marine extract and a method of producing the same are introduced. The marine extract is extracted from cell membranes of marine processing streams, including phosphatidylserine (PS), phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylinositol (PI), and lysophosphatidylcholine (LysoPC), further including at least phosphatidylserine (PS). The aerosol liposome is of a particle diameter of less than 2,000 nm. The surface of the aerosol liposome carries phosphatidylserine (PS) molecules. The aerosol liposome of a marine extract is simple and stable and can be absorbed through the mouth, nose, upper respiratory tract, and epidermis and engulfed by macrophages therein to quickly alleviate or regulate systematic inflammatory responses and prevent inflammation-related diseases.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of producing an aerosol liposome, for producing an marine extract aerosol liposome, comprising the step of atomizing the marine extract into the aerosol liposome with an aerosol atomizer, wherein the marine extract is extracted from cell membranes of marine processing streams, comprises phosphatidylserine (PS), phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylinositol (PI), and lysophosphatidylcholine (LysoPC), includes at least phosphatidylserine (PS), and is characterized in that the aerosol liposome is of a particle diameter of less than 10,000 nm, and a surface of the aerosol liposome carries phosphatidylserine (PS) molecules. 
     
     
         2 . The method of  claim 1 , wherein marine extract-derived solids, a marine extract-containing solvent, and a marine extract suspension are added to an aqueous solution to get diluted and atomized with an aerosol atomizer to synthesize the aerosol liposomes. 
     
     
         3 . The method of  claim 2 , wherein a member selected from the group consisting of the nucleic acid matter, cytokine, and valent ion is added to an aqueous solution.

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