US2019240281A1PendingUtilityA1

Oral anaerobic glutathione supplement in liposome suspension

43
Individually held — no corporate assignee on recordPriority: Feb 17, 2017Filed: Mar 28, 2019Published: Aug 8, 2019
Est. expiryFeb 17, 2037(~10.6 yrs left)· nominal 20-yr term from priority
Inventors:Stephen N. PitcherDanny C. Purser
A61P 7/00A61K 47/46A61K 38/063A61K 47/10A61K 9/0019A61K 47/12A61K 49/1839A61K 9/1271A61K 9/0095A61K 9/127A61K 9/0014
43
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Claims

Abstract

The disclosure relates to compositions, methods and systems for treating cellular oxidative stress in a user. A composition of the disclosure includes an effective amount of reduced glutathione for reducing oxidative stress in the user and a deoxygenated water solvent. The composition is encapsulated in a phospholipid liposome structure and packaged and stored in an airless dispenser configured to maintain an anaerobic environment.

Claims

exact text as granted — not AI-modified
1 . A composition comprising:
 reduced glutathione present in the composition from 5% to 20% by weight of the total composition; and   a deoxygenated water solvent.   
     
     
         2 . The composition of  claim 1 , wherein the composition is encapsulated. 
     
     
         3 . The composition of  claim 2 , wherein the composition is packaged in an airless dispenser configured to maintain an anaerobic environment. 
     
     
         4 . The composition of  claim 2 , wherein the reduced glutathione comprises from about 8% to about 14% by weight of the total composition. 
     
     
         5 . The composition of  claim 2 , where the composition comprises from about 500 mg to about 600 mg reduced glutathione per 4 g of the composition. 
     
     
         6 . The composition of  claim 1 , wherein the reduced glutathione comprises a purity from about 98% to about 99.9% purity. 
     
     
         7 . The composition of  claim 1 , further comprising an effective amount of one or more preservatives selected from a list comprising: potassium sorbate, sodium benzoate, sorbic acid, benzoic acid, natural benzyl alcohol, erythorbic acid, sodium erythorbate, ferrous gluconate, methyl paraben, potassium benzoate, rosemary extract, and sodium citrate. 
     
     
         8 . The composition of  claim 1 , further comprising an effective amount of one or more natural flavoring components for improving an overall flavor of the composition selected from a list comprising: lemon essential oil, peppermint essential oil, monk fruit extract, agave, honey, natural cane sugar, glucose, fruit concentrate, natural fruit powder, spearmint essential oil, wintergreen essential oil, orange essential oil, tangerine essential oil, lavender essential oil, and  stevia  extract. 
     
     
         9 . The composition of  claim 1 , wherein the composition is prepared for liquid oral consumption. 
     
     
         10 . The composition of  claim 1 , wherein the composition is prepared for topical application. 
     
     
         11 . The composition of  claim 1 , wherein the composition is prepared for intravenous or intramuscular administration. 
     
     
         12 . The composition of  claim 1 , wherein the composition comprises from about 4 g to about 20 g reduced glutathione per 100 mL of the deoxygenated water solvent. 
     
     
         13 . A method comprising:
 providing a composition to the user, wherein the composition comprises:
 of reduced glutathione present in the composition from 5% to 20% by weight of the total composition; and 
 a deoxygenated water solvent. 
   
     
     
         14 . The method of  claim 13 , wherein the composition is encapsulated. 
     
     
         15 . The method of  claim 14 , wherein the composition is packaged in an airless dispenser configured to maintain an anaerobic environment. 
     
     
         16 . The method of  claim 14 , wherein the reduced glutathione comprises from about 8% to about 14% by weight of the total composition. 
     
     
         17 . The method of  claim 14 , wherein the composition comprises from about 500 mg to about 600 mg reduced glutathione per 4 g of the composition. 
     
     
         18 . The method of  claim 13 , wherein the reduced glutathione comprises a purity from about 98% to about 99.9% purity. 
     
     
         19 . The method of  claim 13 , wherein the reduced glutathione comprises a purity from about 99.0% to about 99.9% purity. 
     
     
         20 . The method of  claim 13 , wherein the composition further comprises an effective amount of one or more preservatives selected from a list comprising: potassium sorbate, sodium benzoate, sorbic acid, benzoic acid, natural benzyl alcohol, erythorbic acid, sodium erythorbate, ferrous gluconate, methyl paraben, potassium benzoate, rosemary extract, and sodium citrate. 
     
     
         21 . The method of  claim 13 , wherein the composition further comprises an effective amount of one or more natural flavoring components for improving an overall flavor of the composition selected from a list comprising: lemon essential oil, peppermint essential oil, monk fruit extract, agave, honey, natural cane sugar, glucose, fruit concentrate, natural fruit powder, spearmint essential oil, wintergreen essential oil, orange essential oil, tangerine essential oil, lavender essential oil, and  stevia  extract. 
     
     
         22 . The method of  claim 13 , wherein the composition is provided to the user for liquid oral consumption. 
     
     
         23 . The method of  claim 13 , wherein the composition is provided to the user for topical administration. 
     
     
         24 . The method of  claim 13 , wherein the composition is provided to the user for intravenous or intramuscular administration. 
     
     
         25 . The method of  claim 13 , wherein the composition comprises from about 4 g to about 20 g reduced glutathione per 100 mL of the deoxygenated water solvent. 
     
     
         26 . The method of  claim 13 , wherein the composition is provided to the user for short-term treatment of cellular oxidative stress. 
     
     
         27 . The method of  claim 13 , wherein the composition increases blood-serum levels of reduced glutathione in the user by at least 25%. 
     
     
         28 . The method of  claim 13 , wherein the composition is provided to the user for long-term treatment of cellular oxidative stress.

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