Coating film having thinly-spreading and irregularity-conforming properties, and structural base having such film

Abstract

wherein Ua1, Ua2, Ub1, Ub2, Ub3 and An− are as defined herein.

1 . A structural base comprising a coating film on at least a portion of the surface thereof, the coating film having a difference between the maximum film thickness and the minimum film thickness of not more than 1000 Å,
 the coating film comprising a copolymer including a repeating unit containing a group represented by the following formula (a), and a repeating unit containing a group represented by the following formula (b): 
 
       
         
           
           
               
               
           
         
         wherein 
         U a1 , U a2 , U b1 , U b2  and U b3  are each independently a hydrogen atom or a C 1-5  linear or branched alkyl group, and An −  is an anion selected from the group consisting of halide ion, inorganic acid ion, hydroxide ion and isothiocyanate ion. 
       
     
     
         2 . The structural base according to  claim 1 , wherein the copolymer includes repeating units represented by the following formulae (a1) and (b1): 
       
         
           
           
               
               
           
         
         wherein 
         T a  and T b  are each independently a hydrogen atom or a C 1-5  linear or branched alkyl group; 
         Q a  and Q b  are each independently a single bond, an ester bond or an amide bond; 
         R a  and R b  are each independently a C 1-10  linear or branched alkylene group which may be substituted with a halogen atom; 
         U a1 , U a2 , U b1 , U b2  and U b3  are each independently a hydrogen atom or a C 1-5  linear or branched alkyl group; 
         An −  is an anion selected from the group consisting of halide ion, inorganic acid ion, hydroxide ion and isothiocyanate ion; and 
         m is an integer of 0 to 6. 
       
     
     
         3 . The structural base according to  claim 1 , wherein the structural base includes a structural portion composed of at least two flat faces adjacent to one another, the angle between each two of the flat faces being 0<θ<180°. 
     
     
         4 . The structural base according to  claim 1 , wherein the coating film is a biomaterial adhesion inhibitory coating film. 
     
     
         5 . The structural base according to  claim 1 , wherein the structural base is a cell culture vessel and/or an optical measurement base. 
     
     
         6 . The structural base according to  claim 1 , wherein the surface of the structural base has a water contact angle in air of 0 to 120° or a bubble contact angle in water of 80 to 1800. 
     
     
         7 . A method for producing a structural base described in  claim 1 , comprising a step of applying a coating agent onto a structural base in one operation to form a coating film on at least a portion of the surface of the structural base, the difference between the maximum film thickness and the minimum film thickness of the coating film being not more than 1000 Å,
 the coating agent comprising a copolymer including a repeating unit containing a group represented by the following formula (a), and a repeating unit containing a group represented by the following formula (b): 
 
       
         
           
           
               
               
           
         
         wherein 
         U a1 , U a2 , U b1 , U b2  and U b3  are each independently a hydrogen atom or a C 1-5  linear or branched alkyl group, and An −  is an anion selected from the group consisting of halide ion, inorganic acid ion, hydroxide ion and isothiocyanate ion. 
       
     
     
         8 . The production method according to  claim 7 , wherein the copolymer includes repeating units represented by the following formulae (a1) and (b1): 
       
         
           
           
               
               
           
         
         wherein 
         T a  and T b  are each independently a hydrogen atom or a C 1-5  linear or branched alkyl group; 
         Q a  and Q b  are each independently a single bond, an ester bond or an amide bond; 
         R a  and R b  are each independently a C 1-10  linear or branched alkylene group which may be substituted with a halogen atom; 
         U a1 , U a2 , U b1 , U b2  and U b3  are each independently a hydrogen atom or a C 1-5  linear or branched alkyl group; 
         An −  is an anion selected from the group consisting of halide ion, inorganic acid ion, hydroxide ion and isothiocyanate ion; and 
         m is an integer of 0 to 6. 
       
     
     
         9 . The production method according to  claim 7 , wherein the structural base includes a structural portion composed of at least two flat faces adjacent to one another, the angle between each two of the flat faces being 0<θ<180°. 
     
     
         10 . The production method according to  claim 7 , wherein the coating film is a biomaterial adhesion inhibitory coating film. 
     
     
         11 . The production method according to  claim 7 , wherein the water contact angle in air of the surface of the structural base is 0 to 120°, or the bubble contact angle in water of the surface of the structural base is 80 to 180°. 
     
     
         12 . A method for forming a coating film on at least a portion of the surface of a structural base by application and drying operations alone, the difference between the maximum film thickness and the minimum film thickness of the coating film being not more than 1000 Å. 
     
     
         13 . The method according to  claim 12 , wherein the water contact angle in air of the surface of the structural base is 0 to 120° or the bubble contact angle in water of the surface of the structural base is 80 to 180°. 
     
     
         14 . The structural base according to  claim 2 , wherein the structural base includes a structural portion composed of at least two flat faces adjacent to one another, the angle between each two of the flat faces being 0<θ<180°. 
     
     
         15 . The structural base according to  claim 14 , wherein the coating film is a biomaterial adhesion inhibitory coating film. 
     
     
         16 . The structural base according to  claim 15 , wherein the structural base is a cell culture vessel and/or an optical measurement base. 
     
     
         17 . The structural base according to  claim 16 , wherein the surface of the structural base has a water contact angle in air of 0 to 120° or a bubble contact angle in water of 80 to 180°. 
     
     
         18 . The production method according to  claim 8 , wherein the structural base includes a structural portion composed of at least two flat faces adjacent to one another, the angle between each two of the flat faces being 0<θ<180°. 
     
     
         19 . The production method according to  claim 18 , wherein the coating film is a biomaterial adhesion inhibitory coating film. 
     
     
         20 . The production method according to  claim 19 , wherein the water contact angle in air of the surface of the structural base is 0 to 120°, or the bubble contact angle in water of the surface of the structural base is 80 to 180°.