Honey composition with l-alanyl-l-glutamine

Abstract

The present invention relates to compositions including honey and L-alanyl-L-glutamine, pharmaceutical compositions thereof, and a combined product comprising honey and L-alanyl-L-glutamine for a simultaneous, separate, or sequential use in therapy. The composition, pharmaceutical composition, and combined product have particular utility in improving sleep and treating sleep disorders such as insomnia or sleep apnoea.

What is claimed: 
     
         1 . A composition comprising honey and L-alanyl-L-glutamine or pharmaceutically acceptable salts thereof. 
     
     
         2 . The composition of  claim 1 , wherein the composition comprises 1% to 10% L-alanyl-L-glutamine by weight of the composition 
     
     
         3 . The composition of  claim 1 , wherein the composition comprises an effective amount of L-alanyl-L-glutamine that is 10% or less by weight of the composition. 
     
     
         4 . The composition of  claim 1 , further comprising a solvent. 
     
     
         5 . The composition of  claim 1 , further comprising water. 
     
     
         6 . The composition of  claim 1 , further comprising one or more pharmaceutically acceptable diluents, excipients, or carriers. 
     
     
         7 . A method for treating a sleep disorder by administering to a subject suffering from said sleep disorder the composition of  claim 1 . 
     
     
         8 . The method of  claim 5 , wherein the sleep disorder is insomnia. 
     
     
         9 . The method of  claim 5 , wherein the sleep disorder is sleep apnoea. 
     
     
         10 . A method of improving sleep comprising administering to a subject in need thereof the composition of  claim 1 . 
     
     
         11 . The method of  claim 10 , comprising the step of administering the composition to the subject within 30 minutes prior to sleep. 
     
     
         12 . A combined product comprising honey and L-alanyl-L-glutamine or pharmaceutically acceptable salts thereof for simultaneous, separate, or sequential administration. 
     
     
         13 . The composition of  claim 12 , wherein the composition comprises 1% to 10% L-alanyl-L-glutamine by weight of the combined product. 
     
     
         14 . The combined product of  claim 12 , wherein the composition consists essentially of honey and L-alanyl-L-glutamine. 
     
     
         15 . The composition of  claim 12 , further comprising water. 
     
     
         16 . A method for treating a sleep disorder by administering to a subject suffering from said sleep disorder the composition of  claim 12 . 
     
     
         17 . The method of  claim 16 , wherein the sleep disorder is insomnia. 
     
     
         18 . The method of  claim 16 , wherein the sleep disorder is sleep apnoea. 
     
     
         19 . A method of improving sleep comprising administering to a subject in need thereof the composition of  claim 12 . 
     
     
         20 . The method of  claim 19 , comprising the step of administering the composition to the subject within 30 minutes prior to sleep.