US2019192271A1PendingUtilityA1

Cell-containing sheet

Assignee: UNIV NAT CORP TOKYO MEDICAL & DENTALPriority: Jun 17, 2005Filed: Feb 28, 2019Published: Jun 27, 2019
Est. expiryJun 17, 2025(expired)· nominal 20-yr term from priority
A61L 27/3843A61L 27/3808A61L 2430/34C12N 5/0068A61L 27/3604A61F 2/02A61F 2240/001A61L 27/3804A61F 2250/0067A61L 27/58C12N 2533/92A61K 35/12A61F 2210/0076A61L 2430/12C12N 2535/10B82Y 30/00C12N 5/069
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Claims

Abstract

In accordance with the present invention, an implant in which cells are arranged in a fine pattern that is available for immediate implantation and that does not need to be removed after implantation is provided. The present invention relates to a cell-containing sheet, which comprises cells and a support comprising a bioabsorbable material, in which the support has a cell adhesion protein-containing layer on the surface thereof and the cells form a pattern on the support.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A cell-containing sheet, which comprises cells and a support comprising a bioabsorbable material,
 in which the support has a cell adhesion protein-containing layer on the surface thereof and the cells form a pattern on the cell adhesion protein-containing layer, and wherein the support comprises an amnion consisting of stratum compactum and basal lamina.   
     
     
         2 . The cell-containing sheet according to  claim 1 , wherein the support comprises a biodegradable polymer material and the cell adhesion protein-containing layer adhering to the surface of the material. 
     
     
         3 . The cell-containing sheet according to  claim 1 , wherein the cells form cell junctions between each other. 
     
     
         4 . The cell-containing sheet according to  claim 1 , wherein the pattern formed with the cells comprises a pattern with a width of not more than 3 mm. 
     
     
         5 . The cell-containing sheet according to  claim 4 , wherein the pattern formed with the cells comprises lines having widths of 5 μm to 3 mm on which the cells are arranged.

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