US2019185501A1PendingUtilityA1

New molecules from seaweeds with anti-cancer activity

Assignee: OCEANS LTDPriority: Nov 17, 2015Filed: Nov 16, 2016Published: Jun 20, 2019
Est. expiryNov 17, 2035(~9.3 yrs left)· nominal 20-yr term from priority
A61K 9/0053A61K 45/06A61K 31/23A61K 9/48C07C 57/12C07H 15/10A61K 31/122A61P 35/00C07H 3/02C07C 59/42C07C 69/30C07H 15/06A61K 31/7032
47
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Claims

Abstract

The present invention provides purified compounds extracted from seaweeds having the formula (I): wherein R1 and R2 is each independently H or a fatty acid and their use for inhibiting the growth of cancer cells.

Claims

exact text as granted — not AI-modified
1 - 27 . (canceled) 
     
     
         28 . A method of inhibiting a cancer cell comprising contacting said cell with a growth-inhibiting concentration of a compound of formula (I): 
       
         
           
           
               
               
           
         
         wherein R 1  and R 2  is each independently H or a fatty acid selected from the group consisting of: 
       
       
         
           
                 
                 
                 
                 
               
                     
                     
                 
                     
                   Cpd # 
                   R 1   
                   R 2   
                 
                     
                     
                 
                     
                   2 
                   C20:5 
                   C16:0. 
                 
                     
                   7 
                   C20:5 
                   C20:5. 
                 
                     
                     
                 
             
                
                
                
               
               
                
                
                
               
            
           
         
         or a composition comprising said compound in admixture with a physiologically acceptable carrier. 
       
     
     
         29 . A method of treatment of a cancer in a mammal comprising administering a growth-inhibiting concentration of a compound #2 or #7 as defined in  claim 28 , or a composition as defined in  claim 28 . 
     
     
         30 . A gelcap, pill, capsule or other device for oral administration comprising a cancer inhibiting-effective amount of the compound #2 or #7 of  claim 28 . 
     
     
         31 - 34 . (canceled)

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