Blue Light Photobiomodulation

Abstract

The invention is directed to a light source device (10) comprising a light emitting element (12) for emitting a blue light having a wavelength ranging from 435 to 500 nm, the light source device (10) being configured to provide the blue light to at least one cell (C) at a transmitted fluence ranging from 0.01 to 18. J/cm2 to promote or induce growth and proliferation of the cell (C) and wherein the light emitting element (12) has a power density ranging from 0.05 to 30 mW/cm2. The invention is also directed to a light source assembly comprising a product adapted to be in contact with the skin or a wound and a light source device (10) connected to the product for providing blue light to at least one skin cell (C), preferably of the wound.

1 . A light source device comprising a light emitting element for emitting a blue light having a wavelength ranging from 435 to 500 nm, the light source device being configured to provide the blue light to at least one cell at a transmitted fluence ranging from 0.01 to 18.5 J/cm 2  to promote or induce growth and proliferation of the cell and wherein the light emitting element has a power density ranging from 0.05 to 30 mW/cm 2 . 
     
     
         2 . The light source device of  claim 1 , wherein the cell is selected from a skin cell. 
     
     
         3 . The light source device according to  claim 2 , wherein the skin cells are keratinocytes or fibroblasts. 
     
     
         4 . The light source device of  claim 1 , wherein the dominant emission wavelength ranges from 450 to 490 nm. 
     
     
         5 . The light source device according to  claim 1 , wherein the light source device is configured to provide the blue light at a transmitted fluence so that the cell receives an effective fluence ranging from 0.01 to 10 J/cm 2 . 
     
     
         6 . The light source device according to  claim 1 , wherein the light emitting element has a power density ranging from 20 to 25 mW/cm 2 . 
     
     
         7 . The light source device according to  claim 1 , wherein said light emitting element comprises at least one LED. 
     
     
         8 . The light source device according to  claim 1 , further comprising a power source providing electrical power to said light emitting element. 
     
     
         9 . The light source device according to  claim 8 , wherein said power source is a battery. 
     
     
         10 . The light source device according to  claim 1  further comprising at least one among a microchip processor, a control unit, a communication unit, an external port and a sensor. 
     
     
         11 . A light source assembly comprising:
 a product adapted to be in contact with the skin or a wound;   a light source device according to  claim 1  connected to the product for providing blue light to at least one skin cell, preferably of the wound.   
     
     
         12 . The light source assembly according to  claim 11 , wherein the product is one among a dressing, a strip, a compression means, a band-aid, a patch, a gel, a film-forming composition and a rigid or flexible support. 
     
     
         13 . The light source assembly according to  claim 11 , wherein the dressing comprises at least a hydrocolloid or an adhesive layer in contact with the skin or the wound. 
     
     
         14 . The light source assembly according to  claim 11 , wherein the light source assembly is adapted to dispose the light emitting element in a position wherein the light emitting element is facing the skin.