US2019167662A1PendingUtilityA1
Tamper-resistant pharmaceutical compositions of opioids and other drugs
Assignee: COLLEGIUM PHARMACEUTICAL INCPriority: Jul 5, 2002Filed: Jun 25, 2018Published: Jun 6, 2019
Est. expiryJul 5, 2022(expired)· nominal 20-yr term from priority
A61K 9/1641A61K 9/1617A61K 47/44A61K 9/1694A61K 9/4808A61K 31/485A61K 47/12A61P 29/00A61K 9/1664B29C 70/60A61K 9/5042A61K 9/14A61K 9/1635
69
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Claims
Abstract
Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
Claims
exact text as granted — not AI-modified1 . A pharmaceutical composition comprising a plurality of multiparticulates each multiparticulate comprising:
(a) one or more drugs prone to abuse; and (b) one or more excipients comprising fats, fatty substances, waxes, wax-like substances or mixtures thereof; wherein the one or more drugs interact ionically with one or more of the excipients.
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